The role of surgery type in postoperative atrial fibrillation and in-hospital mortality in esophageal cancer patients with preserved left ventricular ejection fraction

Chen, LaiTe; Zhang, Lu; Shi, Lu; Fu, Guosheng; Jiang, Chenyang

doi:10.1186/s12957-020-02011-6

Cited by 4 publications

(1 citation statement)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Reducing the strain on the lung and heart may have led to reduced pulmonary complications and arrhythmias. Moreover, VATS has been reported to significantly reduce the incidence of arrhythmias compared to OE (28). However, the current study is the first to report that RAMIE significantly reduced the incidence of arrhythmias compared to OE and VATS.…”

Section: Discussionmentioning

confidence: 51%

Short-term Outcomes of Robot-assisted Minimally Invasive Esophagectomy Compared With Thoracoscopic or Transthoracic Esophagectomy

et al. 2021

View full text Add to dashboard Cite

Background/Aim: There is no study comparing open esophagectomy (OE), video-assisted thoracic surgery (VATS), and robot-assisted minimally invasive esophagectomy (RAMIE) in a single institution. Patients and Methods: This study included 272 patients who underwent subtotal esophagectomy divided into three groups: OE (n=110), VATS (n=127), and RAMIE (n=35) groups. Moreover, short-term outcomes were compared. Results: Overall complications (CD≥II) were significantly less in the RAMIE than the OE and VATS groups. Recurrent laryngeal nerve paralysis (CD≥II) was significantly lower in the RAMIE than the OE group (p=0.026) and tended to be lower than that in the VATS group (p=0.059). The RAMIE group had significantly less atelectasis (CD≥I and II), pleural effusion (CD≥I and II), arrhythmia (CD≥II), and dysphagia (CD≥II), than both the OE and VATS groups. Conclusion: RAMIE reduced overall postoperative complications after esophagectomy compared with both OE and VATS.Esophageal cancer is the sixth leading cause of cancerrelated mortality worldwide because of its high malignant potential and poor prognosis (1). The postoperative 5-year survival rate in patients with American Joint Committee on Cancer stage I esophageal cancer is approximately 90%. This rate decreases to 45%, 20%, and 10% in patients with stages II, III, and IV diseases, respectively (2). Esophagectomy remains the most efficient treatment option, although chemoradiotherapy may effectively treat esophageal cancer (3). Despite advances in extended lymph node (LN) dissection and perioperative management of esophagectomy, it remains a highly invasive procedure associated with serious postoperative complications (4). The Japanese national database, including 5,354 esophagectomy patients in 713 hospitals in 2011, reported an overall morbidity rate of 41.9% and a 30-day and surgery-related mortality of 1.2% and 3.4%, respectively (5).Thoracoscopic esophagectomy constitutes an attractive and less invasive alternative because esophagectomy with radical lymphadenectomy is one of the most invasive gastrointestinal surgeries (6). Of the patients, 4,209 (66.8%) underwent video-assisted thoracoscopic surgery (VATS). According to a Japanese national database, the ratio increases annually, including 6,298 esophagectomy patients in 2019 (7). Robot assistance provides an enlarged, threedimensional field of view and improves the surgeon's dexterity due to surgical wrists and tremor filtration (8). Multiple retrospective studies have investigated the surgical outcomes of robot-assisted minimally invasive esophagectomy (RAMIE) compared to VATS since its development in 2003 (9-12). A randomized controlled trial reported the benefits of RAMIE over conventional open esophagectomy (OE) in terms of short-term outcomes, and comparable long-term results to OE were found (13).However, there is no study comparing the three techniques of OE, VATS, and RAMIE in a single institution. This study hypothesized that VATS reduced postoperative complications compared to OE. Moreover, RAMIE reduc...

show abstract

Section: Discussionmentioning

confidence: 51%

Short-term Outcomes of Robot-assisted Minimally Invasive Esophagectomy Compared With Thoracoscopic or Transthoracic Esophagectomy

et al. 2021

View full text Add to dashboard Cite

show abstract

Incident Atrial Fibrillation and Survival Outcomes in Esophageal Cancer following Radiotherapy

Miller

McKinley

et al. 2024

International Journal of Radiation Oncology*Biology*Physics

View full text Add to dashboard Cite

Sex differences in survival following surgery for esophageal cancer: A systematic review and meta-analysis

Liatsou,

Bellos,

Katsaros

et al. 2024

Diseases of the Esophagus

View full text Add to dashboard Cite

The impact of sex on the prognosis of patients with esophageal cancer remains unclear. Evidence supports that sex- based disparities in esophageal cancer survival could be attributed to sex- specific risk exposures, such as age at diagnosis, race, socioeconomic status, smoking, drinking, and histological type. The aim of our study is to investigate the role of sex disparities in survival of patients who underwent surgery for esophageal cancer. A systematic review and meta-analysis of the existing literature in PubMed, EMBASE, and CENTRAL from December 1966 to February 2023, was held. Studies that reported sex-related differences in survival outcomes of patients who underwent esophagectomy for esophageal cancer were identified. A total of 314 studies were included in the quantitative analysis. Statistically significant results derived from 1-year and 2-year overall survival pooled analysis with Relative Risk (RR) 0.93 (95% Confidence Interval (CI): 0.90–0.97, I2 = 52.00) and 0.90 (95% CI: 0.85–0.95, I2 = 0.00), respectively (RR < 1 = favorable for men). In the postoperative complications analysis, statistically significant results concerned anastomotic leak and heart complications, RR: 1.08 (95% CI: 1.01–1.16) and 0.62 (95% CI: 0.52–0.75), respectively. Subgroup analysis was performed among studies with <200 and > 200 patients, histology types, study continent and publication year. Overall, sex tends to be an independent prognostic factor for esophageal carcinoma. However, unanimous results seem rather obscure when multivariable analysis and subgroup analysis occurred. More prospective studies and gender-specific protocols should be conducted to better understand the modifying role of sex in esophageal cancer prognosis.

show abstract

The role of surgery type in postoperative atrial fibrillation and in-hospital mortality in esophageal cancer patients with preserved left ventricular ejection fraction

Cited by 4 publications

References 46 publications

Short-term Outcomes of Robot-assisted Minimally Invasive Esophagectomy Compared With Thoracoscopic or Transthoracic Esophagectomy

Short-term Outcomes of Robot-assisted Minimally Invasive Esophagectomy Compared With Thoracoscopic or Transthoracic Esophagectomy

Incident Atrial Fibrillation and Survival Outcomes in Esophageal Cancer following Radiotherapy

Sex differences in survival following surgery for esophageal cancer: A systematic review and meta-analysis

Contact Info

Product

Resources

About