The Role of Technical Quality Control in Histology Laboratories

Abstract

The importance of laboratories cannot be gainsaid as far as the health of any country is concerned. This is especially considering that laboratories have a bearing on the accuracy of research carried out on varied ailments, as well as the effectiveness of any remedial substance. Of course, there are numerous categories of laboratories with histology laboratories coming as some of the most fundamental. Histology laboratories come with a number of distinctive characteristics that can only be comprehended through comparing the laboratories with other areas of medical laboratories. Nevertheless, they also have to ensure the efficacy and integrity of their results. This underlines the importance of quality control in histology laboratories. Quality control underlines a system pertaining to routine technical activities that are aimed at developing and controlling the quality and accuracy of inventory while it is being developed. This system comes up with consistent and routine checks that identify and address omissions and errors, safeguard the integrity, completeness and correctness of data, while also recording all quality control activities.This Review Article examines the role of quality control in histology laboratories. It examines the varied aspects of quality management including risk identification, risk analysis and risk elimination. On the same note, it examines the convergence between quality management and quality assurance while paying close attention to the role of technical quality control in histology laboratories.

Quality Standards of Histopathology Laboratory and Work Facilities in a Developed Country

“…Histology laboratories come with many distinguishing characteristics that can only be understood through equaling the laboratories with other extents of therapeutic laboratories. It is well prominent that quality control checks in histopathology laboratories comprise precise documentation of patients, fixation, appropriate processing, proper procedures for embedding, objectionable artifacts, microtomy, as well as assessments of controls, therefore, to control how proper or accurate protected histochemical techniques and distinct stains are [33] . To work effectively and securely, all the techniques and accomplishments of the histopathology laboratory should be appraised and monitored precisely.…”

“…Safety concerns that may come about in a histopathology lab are principally those interrelated to theoretically dangerous chemicals, biohazardous constituents, accidents accompanying the equipment and musical arrangement employed, and general hazards from electrical and fire exposures [33] . Quality control in histopathology laboratories diminishes the opportunity for the existence of hazards and accidents.…”

Substituição do xilol por óleo de coco extravirgem na etapa de diafanização da rotina histológica

“…Amostras teciduais que devem ser submetidas a exames histológico ou histopatológicos, quando se opta por um método com parafina, precisam passar por uma sequência de procedimentos cujo objetivo é garantir que o fragmento possa ser estudado e na rotina histológica, um tecido mole para se tornar uma lâmina e ser observado em microscopia ótica, passa por várias fases, que vai desde a sua coleta e fixação, passando pela desidratação, diafanização (clarificação), impregnação (inclusão em parafina), microtomia, desparafinização, coloração e montagem, estas etapas conferem suporte ao tecido, além de possibilitar a sua visualização ao microscópio. Neste contexto o xilol é utilizado nas etapas de diafanização, na desparafinação e montagem final das lâminas (Bancroft & Gamble, 2008;Mohammedsaleh, 2014;Patraquim, 2015;Camillo et al, 2017;Do Nascimento et al, 2020), os protocolos dessas etapas dependem ainda do espécime biológico, do tipo de tecido entre outros fatores (Souza et al, 2010).…”