This study analyzes the role of education, training, and e-learning (ETL) in empowering Saudi society, leading to sustainable employment generation in Saudi Arabia. It applies the theory of constructivism, scoping to human aspects of teaching and learning in sustainable employment generation and social empowerment. The study primarily collects the existing variable pools from the available literature on education (EDU), training (TRA), e-learning (ELRN), government policies (GPOL), national culture (NCUL), sustainable employment generation (SUEG), and social empowerment (SEMP). The study performs second-order partial least squares structural equation modeling (PLS-SEM) with moderation analysis. The study aims to obtain the combined effect of ETL on SUEG and SEMP in the presence of GPOL and NCUL in Saudi Arabia. Primarily, the results of the path diagram show that ETL has a significant direct impact on SEMP and SUEG. Secondly, the moderation analysis results show that GPOL has been a significant moderator between ETL and SUEG and ETL and SEMP. In contrast, the analysis results show that the NCUL is not a significant moderator between ETL and SUEG, or between ETL and SEMP. Additionally, the moderation analysis results show that NCUL directly impacts SEMP. In contrast, it does not show a significant direct relationship with SUEG. In the article, the theory of constructivism emphasizes the learners’ active role in constructing knowledge, which is significant for both individuals and society, and the validity of constructed knowledge and its realistic representation in the real world. The practical implementation of the education and e-learning approach of constructivism will help to bridge the gap between the skilled workforce in Saudi Arabia and the rest of the world. Moreover, the students, as learners, will be able to assert their experiences by connecting with the outside world, constructing a sustainable society, leading to sustainable employment generation and social empowerment in Saudi Arabia. The study also has a broad scope for higher educational institutions, training centers, and organizations in Saudi Arabia and the rest of the world.