The role of the haematopoietic tissue in haemocyte production and maturation in the black tiger shrimp (Penaeus monodon)

Braak, C.B.T. van de; Botterblom, M.H.A.; Liu, W.; Taverne, Nico; Knaap, W.P.W. van der; Rombout, J.H.W.M.

doi:10.1006/fsim.2001.0369

Cited by 163 publications

(140 citation statements)

References 24 publications

Supporting

Mentioning

117

Contrasting

Unclassified

Order By: Relevance

“…P. monodon type one cells were considered stem cells that give rise to type two and three cells, whereas type four cells were referred to as interstitial cells. In contrast to other crustaceans, the least-differentiated cells were localized at the exterior of the lobules, whereas more-differentiated cells, types two and three, were localized to the center (van de Braak et al, 2002). Hence, it is clear that additional studies concerning the differentiation process are needed to understand the lineages represented by the different cell types in the HPT and how these cell types develop within this tissue.…”

Section: Cell Types In Hptmentioning

confidence: 88%

“…The lobes are separated from the hemal space by a basal lamina that contains collagen IV (Johnson, 1980). Paired epigastric HPT is present in penaeid shrimps, , and some species might have ancillary sites of HPT surrounding the antennal artery and at the base of the maxillipeds (van de Braak et al, 2002). However, there are large variations in lobule morphology between animals and within tissues, making comparisons difficult (van de Braak et al, 2002).…”

Section: Hematopoietic Tissue (Hpt)mentioning

confidence: 99%

“…Inside the lobules, the predominant cell types were types two or three; both cell types reacted with the Mab WSH8 raised against hemocytes and bound to a 35 kDa antigen (van de Braak et al, 2000(van de Braak et al, , 2002, whereas cell types one and four did not react with WSH8 and were only identified in the HPT (van de Braak et al, 2002). P. monodon type one cells were considered stem cells that give rise to type two and three cells, whereas type four cells were referred to as interstitial cells.…”

Section: Cell Types In Hptmentioning

confidence: 99%

“…An injection of PAMPs might lead to a rapid decrease in circulating hemocytes and thereby stimulate the synthesis and release of new hemocytes in the HPT (Hammond and Smith, 2002;Söderhäll et al, 2003a). Stimulation through LPS and repeated bleeding or the inhibition of mitosis using vinblastine resulted in increased hemocyte release in the penaeid shrimp P. monodon (van de Braak et al, 2002). …”

Section: Reaction To Microbial Polysaccharides and Repeated Bleedingmentioning

confidence: 99%

“…The nature of HCs has been debated; these cells may be immature or prematurely released prohemocytes of the SGC or GC lineage, as suggested (van de Braak et al, 2002) for P. monodon. This view is further substantiated by our studies in P. leniusculus (Lin and Söderhäll, 2011b) and might support previous studies in the swimming crab (Hammond and Smith, 2002).…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Crustacean hematopoiesis

Söderhäll

2016

Developmental & Comparative Immunology

168

138

View full text Add to dashboard Cite

Crustacean hemocytes are important mediators of immune reactions, and the regulation of hemocyte homeostasis is of utmost importance for the health of these animals. This review discusses the current knowledge on the lineages, synthesis and differentiation of hemocytes in crustaceans. Hematopoietic tissues, their origins, and the regulation of hematopoiesis during molting, seasonal variation and infection are discussed. Furthermore, studies concerning the molecular regulation of hemocyte formation in crustaceans are also described, and the different lineages and their molecular markers are discussed and compared with several insect species. Signaling pathways and the regulation of hematopoiesis by transcription factors are typically conserved among these arthropods, whereas cytokines and growth factors are more variable and species specific. However, considering the great diversity among the crustaceans, one should be cautious in drawing general conclusions from studies of only a few species.2

show abstract

Section: Cell Types In Hptmentioning

confidence: 88%

Section: Hematopoietic Tissue (Hpt)mentioning

confidence: 99%

Section: Cell Types In Hptmentioning

confidence: 99%

Section: Reaction To Microbial Polysaccharides and Repeated Bleedingmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Crustacean hematopoiesis

Söderhäll

2016

Developmental & Comparative Immunology

168

138

View full text Add to dashboard Cite

show abstract

Immunology of Invertebrates: Cellular

Smith¹

2010

Encyclopedia of Life Sciences

View full text Add to dashboard Cite

Circulating (free) cells are the main mediators of immunity in invertebrates, carrying out the phagocytic, encapsulating and microbicidal responses that enable these animals to protect themselves against infection without a specific adaptive immune system. The cells are specialised for these functions, with division of labour between types. In general, immune cell diversity tends to increase with body complexity and life histories but common to the majority of species, however, are phagocytic and granular cell types that synthesise and store bioactive proteins. The release of these compounds occurs by exocytosis following interaction of pattern recognition receptors and nonself motifs carried on the surface of pathogens or parasites. Cell death of one form or another appears to be inherent in immune reactivity of many invertebrates with new cells produced, at least in coelomates, by mesodermal haemopoietic tissues. Key concepts Immunity in invertebrates is confined to nonspecific inflammatory responses, mediated to a large extent by the circulating blood cells (haemocytes or coelomocytes) or their products. All coelomate invertebrates contain populations of freely circulating cells dedicated to host defence, some well developed for specialist purposes. There are no true vertebrate‐type lymphocytes and no long‐term, highly specific immune memory in invertebrates. The main invertebrate cellular immune responses include phagocytosis, encapsulation, cytotoxicity and the synthesis and release of microbicidal agents. These cellular reactions often involve the death of immune cells or their removal from the circulation, requiring new cells to be synthesised in the haemopoietic tissue and released into the blood. Genomic and proteomic studies have enabled many of the proteins responsible for cellular defence in invertebrates to be identified, especially in arthropods. Although many of the responses and pathways are ancient and highly conserved, there is great diversity in the effector molecules across the invertebrates as a whole.

show abstract

Immunology of Invertebrates: Cellular

Smith

2016

Encyclopedia of Life Sciences

View full text Add to dashboard Cite

Circulating blood cells are the primary mediators of immunity in invertebrates, carrying out the phagocytic, pathogen trapping and other inflammatory responses that protect invertebrates against infection without specific immunoglobulin antibodies and immune memory. Different immune cell types are usually specialised for different functions with, in general, immune cell diversity tending to increase with body complexity and life history. However, common to most species are phagocytic and/or granular‐type cells that synthesise and store bioactive proteins. Cellular immunity is induced by non‐self motifs on the surface of pathogens or parasites recognised by cell‐derived pattern recognition receptors with diverse binding specificities. Cell death appears to be inherent in immune reactivity of many invertebrates and, in some cases, aids pathogen trapping, which prevents their spread around the body. New immune cells are produced, at least in coelomates, by mesodermal haematopoietic tissues. Key Concepts Immunity in invertebrates is confined to non‐specific inflammatory responses, mediated to a large extent by the circulating blood cells (haemocytes or coelomocytes) or their products. All coelomate invertebrates contain populations of freely circulating cells dedicated to host defence, some well developed for specialist purposes. There are no true vertebrate‐type lymphocytes and no long‐term, highly specific immune memory in invertebrates. The main invertebrate cellular immune responses include phagocytosis, pathogen trapping, cytotoxicity and the synthesis and release of microbicidal agents. These cellular reactions often involve the death of immune cells or their removal from the circulation, requiring new cells to be synthesised in the haemopoietic tissue and released into the blood. Genomic and proteomic studies have enabled many of the proteins responsible for cellular defence in invertebrates to be identified, especially in arthropods. Whilst many of the responses and pathways are ancient and highly conserved, there is great diversity in the effector molecules across the invertebrates as a whole.

show abstract

The role of the haematopoietic tissue in haemocyte production and maturation in the black tiger shrimp (Penaeus monodon)

Cited by 163 publications

References 24 publications

Crustacean hematopoiesis

Crustacean hematopoiesis

Immunology of Invertebrates: Cellular

Immunology of Invertebrates: Cellular

Contact Info

Product

Resources

About