The role of tumor SUVmax/lymph node SUVmax ratio viewed on PET-CT in the detection of mediastinal metastasis in patients with lung cancer

Oztas, Selahattin

doi:10.5606/tgkdc.dergisi.2012.103

Cited by 3 publications

(3 citation statements)

References 24 publications

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“…Although SUV max has no definitive diagnostic value, it has been reported that the SUV max value above 2.5-3 in mediastinal lesions strengthens the likelihood of malignancy. [20] When a SUV max cut-off value of 3 was used in the present study, the sensitivity, specificity, and accuracy of PET/CT in detecting malignancy were 93.5%, 46.1%, and 71.9%, respectively. Furthermore, the SUV max , SUV mean , MTV and HU values were found to be significantly higher in the malignant group than in the benign group in our study, and the optimal cut-off values for SUV max and SUV mean were 4.6 and 3.1, respectively.…”

Section: Discussionmentioning

confidence: 71%

The role of positron emission tomography/computed tomography in the evaluation of anterior mediastinal masses and differentiating between the histological subtypes of thymic epithelial neoplasms

Yanarateş

Budak

2020

Turk Gogus Kalp Dama

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Section: Discussionmentioning

confidence: 71%

The role of positron emission tomography/computed tomography in the evaluation of anterior mediastinal masses and differentiating between the histological subtypes of thymic epithelial neoplasms

Yanarateş

Budak

2020

Turk Gogus Kalp Dama

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“…Data were reconstructed into coronal, sagittal, and transverse sections and a threedimensional rotating projection. SUV-max 2.5 and above for mediastinal lymph nodes were accepted as the cut-off value for malignancy (10).…”

Section: Methodsmentioning

confidence: 99%

Mediastinal lymphnode positivity clinical scoring system for lung adenocarsinoma-mediastinal lymph node evaluation and staging

Ağababaoğlu

Yildiz

Yapar³

et al. 2022

Journal of Health Sciences and Medicine

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Aim: The study-cohort aims to assess PET-CT's correlation with adenocarcinomas' subtypes and propose a scoring system for mediastinal lymph nodes staging. Material and Method: The patient cohort is a multicenter, retrospective analysis of 268 patient that underwent surgery for NSCLC adenocarcinoma. Preoperative PET-CT results for mediastinal lymph node staging was pathologically confirmed on tissue specimens obtained at anatomical resection. Statistical evaluation of PET CT, radiological and pathological outcomes were performed on all subgroups. Results: The low FDG affinity in the lepidic pattern was statistically significant in the study (p

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“…Patients were instructed to fast for six hours before the imaging, and FDG (370 MBq) was administered intravenously. Data were reconstructed into coronal, sagittal, and transverse sections and a three-dimensional rotating projection (11). A comparison was made between the mediastinal lymph node evaluation performed with PET in the preoperative period and the evaluation considered as the gold standard with the postoperative pathology.…”

Section: Pet-ct Imaging Protocolmentioning

confidence: 99%

Effects of EGFR gene mutation on stage 3A lung adenocarcinomas in the clinical decision-making process for mediastinal invasive staging

Ağababaoğlu¹,

Yildiz

Ersöz

et al. 2022

Med Sci Discov

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Objective: In our study, we aimed to evaluate the effects of EGFR gene mutation on the clinical course of Non-Small Cell Lung carcinoma. Material and Methods: Our study was conducted retrospectively on patients who were operated on for NSCLC diagnosed as adenocarcinoma. The International Cancer Control Association and the American Cancer Committee eighth TNM classification system were evaluated in our study. Case groups at this stage were divided into two main groups as EGFR gene mutation (+/-) and data between the clinical behaviours of these two main groups were investigated. Results: There was no statistically significant difference between the two groups in terms of age, gender, smoking, and type of surgery (p = 0.727, p = 0.936, p = 0.463). The relationship between EGFR and surgery type was also not significant (2 = 0.268; p = 0.992). There were no statistically significant difference between the medians of Suv-Max value (z = 1.083; p = 0.279). Among 653 cases in all NSCLC adenocarcinoma subtypes, EGFR gene mutation positivity was 23.89%. When we evaluate the progression of patients with EGFR gene mutation from stage 3A to 3B, it is more aggressive in cases with EGFR gene mutation, but it is not statistically significant (c2=2.924; p=0.087). Conclusions: Knowledge of whether there is an EGFR gene mutation can provide important clinical information. In this respect, EGFR gene mutation positivity in stage 3A cases may constitute an indication for preoperative invasive mediastinal sampling, but we need more data to get statistically definitive results.

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The role of tumor SUVmax/lymph node SUVmax ratio viewed on PET-CT in the detection of mediastinal metastasis in patients with lung cancer

Cited by 3 publications

References 24 publications

The role of positron emission tomography/computed tomography in the evaluation of anterior mediastinal masses and differentiating between the histological subtypes of thymic epithelial neoplasms

The role of positron emission tomography/computed tomography in the evaluation of anterior mediastinal masses and differentiating between the histological subtypes of thymic epithelial neoplasms

Mediastinal lymphnode positivity clinical scoring system for lung adenocarsinoma-mediastinal lymph node evaluation and staging

Effects of EGFR gene mutation on stage 3A lung adenocarcinomas in the clinical decision-making process for mediastinal invasive staging

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