The Role of Venous Constriction in Circulatory Disorders

J, Radó; Gonda, E; Kovács, E

doi:10.1136/hrt.20.3.389

Cited by 8 publications

(1 citation statement)

References 38 publications

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“…In normal subjects and in patients with congestive cardiac failure ganglion blocking agents cause central venous pressure to fall (Restall and Smirk, 1952;Freis et al, 1953;Relman and Epstein, 1949;Smith and Hoobler, 1956;Lyons et al, 1947;Grob and Harvey, 1950;Rado, Gonda and Kovacs, 1958;Halmagyi, et al, 1952). This fall in venous pressure may precede fall of arterial blood pressure and is associated with a decreased cardiac output in the normal subjects (Assali, Douglass and Suyemoto, 1953).…”

Section: Discussion Of Resultsmentioning

confidence: 99%

The Action of Trimetaphan on the Vascular Distensibility of the Hand

Watson

1962

British Journal of Anaesthesia

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The distensibility of the low pressure capacity blood vessels of the human hand was measured by comparing the increase in vascular volume of the hand with the associated increase in vascular distending pressure. The vascular distensibility of the hand was measured in six normal subjects who were initially warm and comfortable. Immersion of the opposite hand in iced water caused the capacity blood vessels of the hand to become less distensible. When trimetaphan was given the capacity vessels became more distensible and less reactive. It is concluded that the capacity vessels of a warm comfortable subject have residual "tone", and that trimetaphan induces hypotension in part by acting upon the systemic capacity vessels. Controlled postural hypotension during anaesthesia is commonly obtained by intravenous infusion of trimetaphan (Arfonad) (Anderson and

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