The role of vitamin D in the onset and progression  of diabetic retinopathy

Totolici, Geanina; Tiutiuca, Carmen; Jurja, Sanda; Tutunaru, Dana; Pătrașcu, Andra-Mădălina

doi:10.22336/rjo.2022.42

Cited by 2 publications

(2 citation statements)

References 35 publications

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“…Vitamin D has properties such as lowering blood glucose, antioxidation, anti-inflammation, antiangiogenesis, and neuroprotection [124][125][126][127].A compelling correlation between serum vitamin D levels and the occurrence or seriousness of DR [128][129][130][131][132][133][134][135][136]. A prospective study found that maintaining adequate optimal levels of vitamin D in the bloodstream can prevent the deleterious impact of diabetes on the intricately interconnected microvasculature, including DR [137].…”

Section: Vitamin Dmentioning

confidence: 99%

Effect of High Sucrose Diet on the Occurrence and Progression of Diabetic Retinopathy and Dietary Modification Strategies

Yang,

Yu,

2024

Preprint

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As the most serious of the many worse new pathological changes caused by diabetes, there are many risk factors for the occurrence and development of DR. It mainly includes hyperglycemia, hypertension, hyperlipidemia and so on. Among them, hyperglycemia is the most critical cause, which plays a key role in the pathological changes of DR.High-sucrose diets(HSDs) lead to elevated blood glucose levels in vivo, which, through oxidative stress, inflammation, the production of AGEs and VEGF, causes plenty of pathological damages to the retina and ultimately bring about loss of vision. The existing therapies for DR primarily target the terminal stage of the disease, when irreversible visual impairment has appeared. Therefore, early prevention is particularly critical. Early prevention of DR-related vision loss requires adjustments to dietary habits, mainly by reducing sugar intake. This article primarily discusses the risk factors, pathophysiological processes, and molecular mechanisms associated with the development of DR caused by HSDs. It aims to raise awareness of the crucial role of diet in the occurrence and progression of DR, promote timely changes in dietary habits, prevent vision loss, and improve the quality of life. The aim is to make people aware of the importance of diet in the occurrence and progression of DR. According to the dietary modification strategies we give, patients can change their poor eating habits timely, avoid the retinopathy that can be avoided theoretically, and obtain a excellent outcome.

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Section: Vitamin Dmentioning

confidence: 99%

Effect of High Sucrose Diet on the Occurrence and Progression of Diabetic Retinopathy and Dietary Modification Strategies

Yang,

Yu,

2024

Preprint

View full text Add to dashboard Cite

show abstract

“…Vitamin D has properties such as lowering blood glucose, antioxidation, anti-inflammation, antiangiogenesis and neuroprotection [133][134][135][136]. There is a compelling correlation between serum vitamin D levels and the occurrence or seriousness of DR [137][138][139][140][141][142][143][144][145].…”

Section: Vitamin Dmentioning

confidence: 99%

Effect of High-Sucrose Diet on the Occurrence and Progression of Diabetic Retinopathy and Dietary Modification Strategies

Yang,

Yu,

2024

Nutrients

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As the most serious of the many worse new pathological changes caused by diabetes, there are many risk factors for the occurrence and development of diabetic retinopathy (DR). They mainly include hyperglycemia, hypertension, hyperlipidemia and so on. Among them, hyperglycemia is the most critical cause, and plays a vital role in the pathological changes of DR. High-sucrose diets (HSDs) lead to elevated blood glucose levels in vivo, which, through oxidative stress, inflammation, the production of advanced glycation end products (AGEs) and vascular endothelial growth factor (VEGF), cause plenty of pathological damages to the retina and ultimately bring about loss of vision. The existing therapies for DR primarily target the terminal stage of the disease, when irreversible visual impairment has appeared. Therefore, early prevention is particularly critical. The early prevention of DR-related vision loss requires adjustments to dietary habits, mainly by reducing sugar intake. This article primarily discusses the risk factors, pathophysiological processes and molecular mechanisms associated with the development of DR caused by HSDs. It aims to raise awareness of the crucial role of diet in the occurrence and progression of DR, promote timely changes in dietary habits, prevent vision loss and improve the quality of life. The aim is to make people aware of the importance of diet in the occurrence and progression of DR. According to the dietary modification strategies that we give, patients can change their poor eating habits in a timely manner to avoid theoretically avoidable retinopathy and obtain an excellent prognosis.

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The role of vitamin D in the onset and progression of diabetic retinopathy

Abstract: This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Cited by 2 publications

References 35 publications

Effect of High Sucrose Diet on the Occurrence and Progression of Diabetic Retinopathy and Dietary Modification Strategies

Effect of High Sucrose Diet on the Occurrence and Progression of Diabetic Retinopathy and Dietary Modification Strategies

Effect of High-Sucrose Diet on the Occurrence and Progression of Diabetic Retinopathy and Dietary Modification Strategies

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