The role of vitamins and micronutrients in the pathogenesis and treatment of vitiligo

Abstract

The active interest of research in the topic of vitiligo is due to the increased possibility of treating this dermatosis of unknown etiology and its high psycho-emotional significance, concerning not only a certain individual, but also affecting society as a whole. The review examines the role of vitamins and micronutrients in the pathogenesis of vitiligo and possible comprehensive approaches to treatment taking into account these elements. Aim: to evaluate the effect of vitamins and micronutrients on the course and development of vitiligo, and also to consider the advisability of their use in the treatment of patients with vitiligo. Materials and methods: A literary review of the PubMed, Cochrane Library, CyberLeninka, Clinicaltrial.gov and the Internet databases was conducted to study the role of specific microelements and vitamins involved in metabolic processes in the development of vitiligo disease. Conclusion. Based on the literature data, we can conclude that vitiligo by etiopathogenesis refers to multifactorial skin diseases, the final consequences of which is the cessation melanogenesis in certain areas of the skin. In all situations, one of the main factors is a metabolic disorder associated with the endoecology of the body. Vitamins and micronutrients play an important role in the pathogenetic chain of vitiligo. Thus, the introduction of individual micronutrients and vitamins into complex therapy of vitiligo seems extremely relevant and promising.