This paper is focused on the application of concepts derived from metamaterials to the development of novel devices, circuits, and antennas of interest in wireless communications, radiofrequency identification (RFID), and sensors. Specifically, it is shown that artificial transmission lines based (or inspired) on metamaterials exhibit interesting properties, useful for the implementation of high-performance and compact devices as well as novel functional devices. Thanks to the presence of reactive loading elements in such artificial lines, the main line parameters, that is, the characteristic impedance and the phase constant, can be engineered. This has opened new paths for RF and microwave circuit and antenna design on the basis of impedance and dispersion engineering.