THE ROSENMUND-von BRAUN NITRILE SYNTHESIS¹

Versatility of Terpyridine‐Functionalised Aryl Tetrazoles: Photophysical Properties, Ratiometric Sensing of Zinc Cations and Sensitisation of Lanthanide Luminescence

“…An alternative sequence was followed for the preparation of H TzPyTpy (Figure ). Firstly, 2‐cyanopyridine‐5‐carboxyalhedyde, NC Py CHO, was prepared by reaction of 2‐bromopyridine‐5‐carboxyalhedyde with copper(I) cyanide in DMF, according to a previously published procedure . A 1,3‐dipolar cycloaddition reaction was then performed on NC Py CHO for the formation of the tetrazole ring in H TzPy CHO .…”

“…General Considerations: All reagents and solvents were purchased from Sigma Aldrich and were used as received, without further purification. The [Ln(NO 3 ) 3 (DMSO) n ] (Ln 3+ = Gd 3+ , Eu 3+ , Yb 3+ ), NC PhTpy and NC Py CHO precursors were prepared according to previously published procedures. Nuclear magnetic resonance spectra, consisting of 1 H NMR and 13 C NMR, were recorded with a Bruker Avance 400 spectrometer (400.1 MHz for 1 H, 100 MHz for 13 C) at 300 K. The 1 H NMR and 13 C NMR chemical shifts were referenced to residual solvent signals.…”

“…Firstly, 2-cyanopyridine-5-carboxyalhedyde, NCPyCHO, was prepared by reaction of 2-bromopyridine-5-carboxyalhedyde with copper(I) cyanide in DMF, according to a previously published procedure. [26] A 1,3-dipolar cycloaddition reaction was then performed on NCPyCHO for the formation of the tetrazole ring in HTzPyCHO. [23] The species HTzPy-CHO was analysed by IR spectroscopy and 1 H NMR and 13 C NMR spectroscopy.…”

The Inhibited Autoxidation of Styrene: Part Iii. The Relative Inhibiting Efficiencies of Ortho-Alkyl Phenols

“…The exception, 2-t-butyl-4-cyanophenol (white needles from n-hexane, m.p. 163-164' C), was prepared from 2-t-butyl-4-bromophenol by the Rosenmund -von Braun nitrile synthesis (6). All the phenols were checked for purity by gas chromatography before use.…”

Catalytic Hydrogen Production by Ruthenium Complexes from the Conversion of Primary Amines to Nitriles: Potential Application as a Liquid Organic Hydrogen Carrier

“…[23][24][25][26][27] In this work, we have evaluatedt he potential of the amine/nitrile paira saliquid organic hydrogen carrier,a s suggested by Grelliera nd Sabo-Etienne in af rontier-type article (Scheme 1). [36,37] An ovel and green method for the synthesis of nitrilesc onsists in the acceptorless dehydrogenation of primary amines. The reaction is not favored at room temperature and an effective catalyst is neededf or practical purposes.E fficient catalysts for the acceptorless dehydrogenationo fa mines are scarce and were first developedb yt he group of Szymczak based on ar uthenium pincer complex.…”