The safety and diagnostic value of frame-based and ct-guided stereotactic brain biopsy technique

Computerized tomography guided stereotactic biopsy of intracranial lesions: report of consecutive 500 cases.

“…Stereotactic biopsy (SB) has been one of the techniques to make a diagnosis, which ensures the implementation of appropriate treatment modality in brain lesions especially after the use of CT (2,4,(7)(8)(9)(11)(12)(13)15,16,18,19,21,22,25,26,28,29,(31)(32)(33)(34)(35)(36)(37)(38). It is a reliable and safe diagnostic method which is preferred especially in deeply placed, widespread and multiple lesions.…”

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ABSTRACT mass should not be taken in consideration, especially in the diagnosis of deeply located, diffused infiltrative or multiple space-occupying lesions, computerized tomography (CT) or MRI-guided stereotactic biopsies have been proven to be safe and reliable by various studies (2,4,(7)(8)(9)(11)(12)(13)15,16,18,19,(21)(22)(23)(25)(26)(27)(28)(29)(31)(32)(33)(34)(35)(36)(37)(38)

Despite the tremendous improvement in neuroradiology and nuclear medicine, especially in magnetic resonance imaging (MRI) and positron emission tomography (PET), definitive diagnosis in most brain lesions require histopathological examination. When a bulk excision of the AIm: Computed tomography (CT)-guided stereotactic brain biopsy has been performed in our clinic since March 1998.

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CT-guided Stereotactic Microsurgical Resection of Cerebral Mass Lesions

“…Meanwhile, Leksell established the basis of a novel system combining the cartesian system with other systems, which consisted of an apparatus fixed to Guiot et al 6,7 and Riechert and Mundinger 8 were the first investigators to introduce open stereotactic craniotomy, which was then enjoyed broader applications and further refinements owing to the advances in the field of medical imaging such as computerized tomography 9 and magnetic resonance imaging 10 . Current image-guided stereotactic procedures include biopsy [11][12][13][14][15] , cyst aspiration 16,17 , focal irradiation 18,19 , and hematoma evacuation [20][21][22] , neuroaugmentation 22,23 , stereotactic robotic microsurgery [24][25][26] and neural transplantation 27,28 . These techniques facilitate precise localization and resection of lesions in eloquent regions of brain and help minimize operative injury to the surrounding tissues.…”

Stereotactic Brain Biopsy or Bronchoscopic/Transthoracic Needle Biopsy for Diagnosis of Metastatic Cancer Presenting Simultaneously in Lung and Brain: A Comparison of Safety and Efficacy

“…A recent review of 290 cases of CT guided biopsy reported a diagnostic biopsy in 95.5%, a 4.1% incidence of symptomatic hemorrhage (two required surgery), and a mortality of 0.8% (Ersahin et al, 2011). A recent series of 134 patients done without frozen section confirmation had a diagnostic yield of 99.3% (one targeting error) and complications in 2.2%, one of which was a conservatively treated hematoma and two of which were fatal in high grade gliomas (1.5%) (Shooman, Belli, & Grundy, 2010).…”