The safety and efficacy of the LVIS stent for the treatment of ruptured intracranial aneurysms within 24 hours: A multicenter retrospective study

Perioperative complications of arteriovenous tirofiban administration versus oral dual antiplatelet therapy for stent‐assisted embolization treated aneurysmal subarachnoid hemorrhage: A retrospective, controlled cohort analysis

“…Perioperative TEs were defined as any angiographic filling defect of the aneurysm‐carrying artery or distal arteries during DSA examination and treatment or new ischemic symptoms such as consciousness changes and limb movement changes in the 72‐h postoperative period with new low‐density shadows or ischemic spots in the vascular distribution area (excluding vasospasm) as clarified by CT or MRI (Wang et al., 2020 ). Perioperative HEs were defined as contrast extravasation or herniation of the coil out of the aneurysm capsule during DSA examination and treatment; new intracranial hemorrhage with or without certain clinical symptoms on postoperative head CT/MRI; and other severe bleeding events, such as severe gastrointestinal bleeding, respiratory bleeding, and multiple skin petechiae ecchymoses (Wu et al., 2021 ).…”

Predictors of thromboembolic complications after stent-assisted coiling of acutely ruptured intracranial aneurysms: A retrospective multicenter study

“…The institutional review board approved this study, and the informed consent was waived. This retrospective multicenter study focused on patients with acutely ruptured aneurysms treated with LVIS stents ( 13 ). One hundred and ten consecutive patients with ruptured aneurysms performed SAC within 72 h of the onset between January 2017 to December 2017.…”

“…The primary outcome was the thromboembolic complication. The thromboembolic complications were defined as angiographic filling defects at the aneurysms base or the distal artery during the stent treatment and the new onset of symptomatic ischemia and a new hypo-density in parent and distal arteries distribution in the first 24 h after the procedure ( 13 ). Angiograms and CT scans were reviewed by both independent interventional neuroradiologist and neurosurgeon who were not involved in the treatment.…”

Stent-assisted coiling of acutely ruptured cerebral aneurysm: a multicenter prospective registry study (SAVE)

“…There are two standard protocols for antiplatelet therapy for the stent deployment One is a loading dose of 300 mg clopidogrel and 300 mg of aspirin given through a nasogastric tube or rectally before 2 hours of the stent usage. The other is an 8–10 u g/kg loading dose of tirofiban for 3 min administered intravenously during the stent deployment followed by a 0.10 μg/kg/min maintenance [ 6 , 10 , 11 ]. A dose of 100 mg aspirin and 75 mg clopidogrel (traditional dual antiplatelet therapy) is given daily for 3 months after the procedure.…”

“…With the advancement of technologies, stent-assisted coiling (SAC) has been widely reported for the treatment of cerebral aneurysms, especially unruptured aneurysms with a good imaging follow-up [ 4 , 5 ]. Although our previous study has shown that SAC may be safe and effective in the treatment of selected patients with acutely ruptured aneurysms [ 6 ], SAC of wide-neck ruptured aneurysms still remains controversial because of an uncertain rate of procedure-related complications and a lack of high-level clinical evidence [ 4 , 5 , 7 – 9 ].…”