Establishing a safe pneumoperitoneum in laparoscopic surgery is the beginning of the surgery. This study aimed to compare Veress needle insertion (VNI) and direct trocar insertion (DTI) methods. Methods: A total of 122 patients who underwent laparoscopic intervention mainly laparoscopic cholecystectomy, between August 2017 and February 2018, in the general surgery clinic were randomized. Among all patients, 62 were insufflated and operated using VNI and 60 with DTI method. The number of laparoscopic entrances, time of entry, complications, and postoperative pain were compared between the groups. Results: The two groups were similar in terms of demographic characteristics. A statistically significant difference was observed between the DTI and VNI groups regarding the entry time, pneumoperitoneum formation time, and gas leakage variables. A statistically significant difference was also observed between the DTI and VNI groups in the number of insertions. For the other variables, no statistically significant difference was observed between the DTI and VNI groups. Conclusion: In DTI, the duration of the generation of the pneumoperitoneum was significantly shorter. However, gas leakage was higher in the DTI group. No significant difference was observed in other variables. The DTI may be preferable to VNI according to time.