The safety evaluation of Dunaliella bardawil as a potential food supplement

Mokády, Shoshana; Abramovici, Armand; Cogan, Uri

doi:10.1016/0278-6915(89)90159-2

Cited by 42 publications

(28 citation statements)

References 7 publications

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“…This is in general agreement with the values reported herein. Whereas, our values for kidney weight, as a percentage of body weight, were much smaller than 0.78-0.86% for control and 0.60-0.79% reported by Mokady et al (1989) for rats fed D. bardawil for 1 year. The testis weight, as percent body weight, increased significantly with the increase in the level of acacia (Table 4).…”

Section: Study Of the Internal Organs Of F 0 Ratscontrasting

confidence: 79%

“…The ovary was not weighed since a preliminary study did not indicate any histological effect of acacia incorporation at 40% in the diet of female rats. Mokady et al (1989) using Charles River CD strain of rats reported the liver weight as 2.93-3.08% of the body weight of the male and 3.26-3.74% for female rats fed an experimental Dunaliella bardawil (algae) diet for 1 year. This is in general agreement with the values reported herein.…”

Section: Study Of the Internal Organs Of F 0 Ratsmentioning

confidence: 99%

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Reproductive performance of Wistar rats fed Acacia colei seed-based diets

Adewusi

Falade

Nwoha

et al. 2006

Journal of Arid Environments

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Section: Study Of the Internal Organs Of F 0 Ratscontrasting

confidence: 79%

Section: Study Of the Internal Organs Of F 0 Ratsmentioning

confidence: 99%

Reproductive performance of Wistar rats fed Acacia colei seed-based diets

Adewusi

Falade

Nwoha

et al. 2006

Journal of Arid Environments

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“…Since Dunaliella is reported to be safe for consumption as reported by studies using animals [27], it can be possibly utilized for such preparations requiring antihepatotoxic activity.…”

Section: Discussionmentioning

confidence: 98%

Protective effect of —A marine micro alga, against carbon tetrachloride-induced hepatotoxicity in rats

Murthy

Rajesha

Vanitha

et al. 2005

Hepatology Research

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“…Determination of protein concentration was done using bovine serum albumin as standard (15) while serum globulin was estimated using the method of Mokady et al (16). Albumin concentration in the serum was measured using the bromocrecsol green method (17).…”

Section: Determination Of Biochemical Parametersmentioning

confidence: 99%

Methanolic leaf extract of <i>Ficus exasperata</i> attenuates Arsenate–mediated hepatic and renal oxidative stress in rats

Oyewole¹,

Oladele²,

Oladele³

2017

Research Journal of Health Sciences

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Objective: In furtherance of the scientific search for suitable antidotes for pro-oxidative toxicants which man is exposed to on daily basis, the study investigated the modulatory potential of Ficus exasperata leaf extract on arsenate-mediated hepatic and renal toxicity using rats as a model. Methodology:Twenty-eight rats were sorted into four groups containing seven rats each. Group A (control) received distilled water while 10 mg/kg bw of sodium arsenate was administered intraperitoneally to groups B, C and D to induce hepatic and renal damage. Group C and D were treated with oral administration of 100 mg/kg bw and 200 mg/kg bw of methanolic leaf extract of Ficus exasperata respectively for 14 days.Results: Arsenate significantly (P? 0.05) induced hepatic and renal damage characterized by elevated levels of serum urea, creatinine, uric acid, alanine aminotransferase (ALT) and aspartate aminotransferase (AST). Arsenate also caused decreased serum concentrations of albumin, globulin and total protein as well as significant depletion in antioxidant status (glutathione-S-transferase (GST), superoxide dismutase (SOD) and catalase (CAT) in the liver and kidney of the rats. Administration of leaf extract of Ficus exasperata significantly (P? 0.05) attenuated all these toxic effects by boosting antioxidants status and normalizing serum hepatic and renal markers. Conclusion:These results are indicative of the modulatory potential of Ficus exasperata leaf on liver and kidney dysfunction arising from oxidative damage.

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The safety evaluation of Dunaliella bardawil as a potential food supplement

Cited by 42 publications

References 7 publications

Reproductive performance of Wistar rats fed Acacia colei seed-based diets

Reproductive performance of Wistar rats fed Acacia colei seed-based diets

Protective effect of —A marine micro alga, against carbon tetrachloride-induced hepatotoxicity in rats

Methanolic leaf extract of <i>Ficus exasperata</i> attenuates Arsenate–mediated hepatic and renal oxidative stress in rats

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