The Safety of a Vegan Diet During Pregnancy

Miedziaszczyk, Miłosz; Ciabach, Patrycja; Grześkowiak, Edmund; Szałek, Edyta

doi:10.5604/01.3001.0014.9343

Cited by 6 publications

(4 citation statements)

References 59 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This reducing effect, in turn, should result in an increase in plasma drug level [ 50 , 51 , 52 ]. However, the aforementioned inhibitory effect is not shared by all the components of botanical supplements and may differ between particular substances [ 53 , 54 ]. In one case report [ 18 ], researchers observed an increase in tacrolimus levels following green tea ingestion, and its normalization after the tea was discontinued.…”

Section: Resultsmentioning

confidence: 99%

Controversial Interactions of Tacrolimus with Dietary Supplements, Herbs and Food

Miedziaszczyk

Bajon²,

Jakielska³

et al. 2022

Pharmaceutics

View full text Add to dashboard Cite

Tacrolimus is an immunosuppressive calcineurin inhibitor used to prevent rejection in allogeneic organ transplant recipients, such as kidney, liver, heart or lung. It is metabolized in the liver, involving the cytochrome P450 (CYP3A4) isoform CYP3A4, and is characterized by a narrow therapeutic window, dose-dependent toxicity and high inter-individual and intra-individual variability. In view of the abovementioned facts, the aim of the study is to present selected interactions between tacrolimus and the commonly used dietary supplements, herbs and food. The review was based on the available scientific literature found in the PubMed, Scopus and Cochrane databases. An increase in the serum concentration of tacrolimus can be caused by CYP3A4 inhibitors, such as grapefruit, pomelo, clementine, pomegranate, ginger and turmeric, revealing the side effects of this drug, particularly nephrotoxicity. In contrast, CYP3A4 inducers, such as St. John’s Wort, may result in a lack of therapeutic effect by reducing the drug concentration. Additionally, the use of Panax ginseng, green tea, Schisandra sphenanthera and melatonin in patients receiving tacrolimus is highly controversial. Therefore, since alternative medicine constitutes an attractive treatment option for patients, modern healthcare should emphasize the potential interactions between herbal medicines and synthetic drugs. In fact, each drug or herbal supplement should be reported by the patient to the physician (concordance) if it is taken in the course of immunosuppressive therapy, since it may affect the pharmacokinetic and pharmacodynamic parameters of other preparations.

show abstract

Section: Resultsmentioning

confidence: 99%

Controversial Interactions of Tacrolimus with Dietary Supplements, Herbs and Food

Miedziaszczyk

Bajon²,

Jakielska³

et al. 2022

Pharmaceutics

View full text Add to dashboard Cite

show abstract

“…[32] Adhering to plant-based diets during pregnancy and lactation necessitates a heightened consciousness of consuming all necessary critical nutrients and vitamin supplements. This is because vitamin B12, vitamin D, iron, and folic acid are crucial for maintaining a healthy pregnancy and promoting optimal fetal growth [39].…”

Section: Vegetarianism During Pregnancymentioning

confidence: 99%

Vegetarian Diet in Children: Benefits, Drawbacks and Risks

Orzeł,

Sieniawska,

Sieniawska

et al. 2024

J Educ Health Sport

View full text Add to dashboard Cite

Introduction Vegetarianism is an eating pattern centred on plant-based food. It encompasses many diets that differ in terms of whether they contain goods originating from animals, like milk and eggs. Nowadays, vegetarianism is increasing in popularity in developed nations, particularly in Europe. Individuals choose vegetarian diets for reasons related to health, ethics, or ecology. The rising popularity of vegetarian diets is not limited to adults but is also increasing among children. Aim of the study Vegetarian diets are generally considered to be beneficial for health. However, there are concerns over the ability to meet the dietary requirements necessary during infancy, youth, and adolescence on a vegetarian diet. Therefore, the primary aim of this systematic review is to answer questions about the efficacy of a plant-based diet in meeting the nutritional requirements of children and how to avoid the risk of nutritional deficiencies among vegetarian children. Material and methods Article provides an overview of the current literature about the vegetarian diet in children. The information has been collected from a comprehensive search of electronic databases, scientific journals, and statement papers published by nutrition and paediatric organisations. Results Following a vegetarian diet can be a beneficial decision for all children, assuming that it is properly organised and well balanced. The majority of paediatric and nutrition organisations do not recommend more strict diets for children, such as a vegan diet, which fully excludes not only meat but all animal products.

show abstract

“…Another type of vegetarian diet is pescetarianism, which also includes fish. In contrast, in a vegan diet, only the consumption of fruits and vegetables is allowed [ 3 , 4 ]. Vegetarian diet types are summarized in Table 1 .…”

Section: Introductionmentioning

confidence: 99%

The impact of a vegetarian diet on chronic kidney disease (CKD) progression – a systematic review

et al. 2023

Self Cite

View full text Add to dashboard Cite

Background A vegetarian diet is a popular alternative to the casual diet - it is considered healthy, and was proven to positively affect cardiovascular health. The Chronic Kidney Disease (CKD) progression is a major issue in the healthcare system, and constitutes a leading cause of death for 1.5% of the global population. The objective of this systematic review was to investigate the potential impact of a vegetarian diet on kidney function in CKD patients. Method Our systematic review focused on randomized controlled trials (RCTs) which compared the effects of a vegetarian diet (experimental) and a standard omnivore diet (comparator) in terms of the estimated glomerular filtration rate (eGFR) in CKD patients. Inclusion criteria were based on PICO elements, with two researchers involved in browsing the Cochrane and Pubmed search engines. The investigation was performed using the PRISMA 2020 Checklist and PRISMA 2020 flow diagram. The search terms included: ‘vegetarian diet’ AND ‘nephropathy’, ‘eGFR’, ‘albuminuria’, ‘chronic kidney disease’. Bias assessment was performed using RoB 2 tool to determine the validity of the data collected from studies. Results Four RCTs with a total of 346 participants were included in the presented systematic review. Two largest RCTs reported an increase in eGFR following a change to a vegetarian diet (p = 0.01 and p = 0.001). Another two found no significant differences between the experimental and control groups, also these trials were associated with a high risk of bias in terms of missing data outcome and the randomization process. Conclusions The findings collected in this systematic review suggest that a vegetarian diet improves renal filtration function in CKD patients. Therefore, it seems essential to conduct further research involving the impact of the diet on the progression of CKD.

show abstract

The Safety of a Vegan Diet During Pregnancy

Cited by 6 publications

References 59 publications

Controversial Interactions of Tacrolimus with Dietary Supplements, Herbs and Food

Controversial Interactions of Tacrolimus with Dietary Supplements, Herbs and Food

Vegetarian Diet in Children: Benefits, Drawbacks and Risks

The impact of a vegetarian diet on chronic kidney disease (CKD) progression – a systematic review

Contact Info

Product

Resources

About