“…Since the optimal yield is to obtain the maximal amount of information by recording seizures while minimizing the stay in the hospital, provocative procedures to elicit seizures, such as tapering of antiepileptic drugs, sleep deprivation, and hyperventilation, are commonly used. However, this practice may expose patients to potentially serious adverse events (SAEs) that have recently caught attention and raised concerns about patients' safety in EMUs [3][4][5][6][7][8][9][10][11][12][13][14]. The International League Against Epilepsy [1], the American Clinical Neurophysiological Society [15], and the National Association of Epilepsy Centers [16] have issued guidelines and recommendations regarding the clinical indications and the requirements for LTM in EMUs, which only marginally dealt with safety issues.…”