2023
DOI: 10.3389/fcvm.2023.1111538
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The saga of dyssynchrony imaging: Are we getting to the point

Abstract: Cardiac resynchronisation therapy (CRT) has an established role in the management of patients with heart failure, reduced left ventricular ejection fraction (LVEF < 35%) and widened QRS (>130 msec). Despite the complex pathophysiology of left ventricular (LV) dyssynchrony and the increasing evidence supporting the identification of specific electromechanical substrates that are associated with a higher probability of CRT response, the assessment of LVEF is the only imaging-derived parameter used … Show more

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Cited by 6 publications
(1 citation statement)
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“…In the last three decades, extensive research efforts have focused on identifying imaging-based parameters that can uncover the electromechanical factors influencing the effectiveness of cardiac resynchronization therapy (CRT) [ 17 ]. Echocardiographic assessment of ventricular or mechanical dyssynchrony before CRT, irrespective of left ventricular ejection fraction (LVEF) or QRS duration [ 18 , 19 , 20 ] may enhance patient selection and identify patients who may benefit from CRT [ 9 , 21 ].…”
Section: Introductionmentioning
confidence: 99%
“…In the last three decades, extensive research efforts have focused on identifying imaging-based parameters that can uncover the electromechanical factors influencing the effectiveness of cardiac resynchronization therapy (CRT) [ 17 ]. Echocardiographic assessment of ventricular or mechanical dyssynchrony before CRT, irrespective of left ventricular ejection fraction (LVEF) or QRS duration [ 18 , 19 , 20 ] may enhance patient selection and identify patients who may benefit from CRT [ 9 , 21 ].…”
Section: Introductionmentioning
confidence: 99%