The Salmonella mutagenicity of water and sediments from the Porsuk River in Turkey

Kutlu, Hatice Mehtap; Aydoğan, Gözde; Susuz, F.; Özata, Ahmet

doi:10.1016/j.etap.2004.03.005

Cited by 14 publications

(7 citation statements)

References 20 publications

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“…Desta forma, considerando que outros trabalhos comprovam a atividade citotóxica e mutagênica de amostras de rios que sofrem com descarga de efluentes industriais e domésticos (GANA et al, 2008;KUTLU et al, 2004), outros estudos podem ser realizados na região do Rio do Peixe-SP, com a finalidade de monitorar a citotoxicidade e mutagenicidade dessas águas, em diferentes estações do ano.…”

Section: Ponto Deunclassified

Citotoxicidade das águas do Rio do Peixe (São Paulo-Brasil), em células meristemáticas de raiz de Allium cepa L.

Costa¹

2015

Biosci. J.

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RESUMO: Nas últimas décadas, a qualidade da água do Rio do Peixe, localizado no interior do Estado de São Paulo, está diminuindo, principalmente porque o rio vem sofrendo com o desmatamento feito às suas margens, o que provocou o assoreamento e permitiu o despejo de todos os tipos de resíduos, em especial das indústrias que ficam ao seu redor. Assim, o objetivo deste trabalho foi avaliar o potencial citotóxico das águas do Rio do Peixe, coletadas em quatro propriedades rurais localizadas em Garça-SP (nascente), Tupã-SP, Flórida Paulista-SP e Ouro Verde-SP (jusante), usando como sistema teste vegetal as células meristemáticas de raiz de Allium cepa L. Os resultados obtidos mostraram que todas as amostras das águas coletadas não apresentaram efeito citotóxico após 24 horas de tratamento. Entretanto, as amostras obtidas em Tupã, Flórida Paulista e Ouro Verde (jusante) foram mutagênicas, pois causaram o aparecimento de alterações nas células, principalmente, dos tipos metáfases-colchicínicas, anáfases desorganizadas, multipolares e com ponte cromatídica, além de células micronucleadas. Portanto, os resultados obtidos alertam para o perigo eminente que os efluentes lançados indiscriminadamente no ambiente, de rios e lagos, podem representar não só aos organismos que ali habitam, mas a todos os outros que dele dependem, seja para lazer, limpeza, higiene ou alimentação.

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Section: Ponto Deunclassified

Citotoxicidade das águas do Rio do Peixe (São Paulo-Brasil), em células meristemáticas de raiz de Allium cepa L.

Costa¹

2015

Biosci. J.

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“…A sample was considered positive when the MI was equal to or greater than 2 for at least one of the tested doses and if it had a reproducible dose-response 21) . Several authors have used this parameter in their works [22][23][24][25] . According to Mortelmans and Zeiger 26) , in an important review of the Ames test a widely used approach is to analyze the results and to set a minimum fold increase, usually 2-3 folds, in revertants (over the solvent control) as a cut-off between mutagenic and nonmutagenic responses.…”

Section: Mutagenicity Testmentioning

confidence: 99%

Urinary Mutagenicity in Chemical Laboratory Workers Exposed to Solvents

Varella

Rampazo

Varanda

2008

Journal of Occupational Health

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“…It should be pointed out that the Ames test was to identify the most significant sites for initial assessment of the basin presence of mutagenic compounds (Vargas et al, 1993). Ames test was performed on water and sediment samples from Porsuk River without metabolic activation using TA98 and TA100 strains and found mutagenic and toxic effects with both strains at 5 different concentrations and in different sampling sites (Kutlu et al, 2004). One study in India reported the extracts of the Penobscot River water and sediments and Penobscot drinking water had little to no mutagenic activity using the Salmonella mutagenicity assay detects (Warren et al, 2015).…”

Section: Discussionmentioning

confidence: 99%

“…Identifying the pollution, especially if caused by organic chemicals, is not economically and practically cost-effective due to the complex molecular structure of organic chemicals in the aquatic environment. Among these pollutants, the detection of mutagenes in aquatic environment is of great importance because of their abilities to induce cancer and potential damage to the germ line, which may lead to fertility problems and genetic damages among the future generations (Kutlu et al, 2004). Therefore, short-term bioassays coupled with chemical analysis are a valuable technique to assessing toxic components in environmental samples (Schuetzle and Lewtas, 1986).…”

Section: Introductionmentioning

confidence: 99%

The mutagenicity of organic extracts in source water and peripheral water with different disinfection ways

Zhong

Huang³

et al. 2019

Appl Env Biotechnol

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This study aimed to determine mutagen contamination, to compare the differences between inlet and outlet distribution, and the possible impacts on public health. Water samples were collected from four different waterworks in Guangzhou, China. The Ames test was conducted to investigate the potential mutagenicity caused by organic extracts from drinking water sources and peripheral water. Organic content was extracted with XAD-2 resin column and organic solvents, and toxicity was tested in three doses of extract equivalent, 0.2, 0.4 and 0.8 L source water. The results of the Ames test showed that all the organic extracts from water samples could induce different levels of mutagenic potentials in the absence of S9 mix, which indicated mutagenicity and strain. Comparing with TA98, TA100 was more sensitive in genotoxicity. Mutagenic enhancement factors were found in both drinking water sources and peripheral water. Water treatment technologies with different disinfection ways could increase the mutagenicity of water, but the biological significance of mutagenicity of the organic extracts remained to be further confirmed. The results suggested that it was necessary to concern the relationship between source water, water treatment unit and the mutagenicity factors of water.

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The Salmonella mutagenicity of water and sediments from the Porsuk River in Turkey

Cited by 14 publications

References 20 publications

Citotoxicidade das águas do Rio do Peixe (São Paulo-Brasil), em células meristemáticas de raiz de Allium cepa L.

Citotoxicidade das águas do Rio do Peixe (São Paulo-Brasil), em células meristemáticas de raiz de Allium cepa L.

Urinary Mutagenicity in Chemical Laboratory Workers Exposed to Solvents

The mutagenicity of organic extracts in source water and peripheral water with different disinfection ways

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