Suppose that X and Y are Banach spaces complemented in each other with supplemented subspaces A and B. In 1996, W. T. Gowers solved the Schroeder-Bernstein problem for Banach spaces by showing that X is not necessarily isomorphic to Y . In this paper, we obtain some suitable conditions involving the spaces A and B to yield that X is isomorphic to Y or to provide that at least X m is isomorphic to Y n for some m, n ∈ IN * . So we get some decomposition methods in Banach spaces via supplemented subspaces resembling Pe lczyński's decomposition methods. In order to do this, we introduce several notions of Schroeder-Bernstein Quadruples acting on the spaces X, Y , A and B. Thus, we characterize them by using some Banach spaces recently constructed.