The Scientific Analysis of physical anaphylaxis and FDEIAn

Abstract

PURPOSE: It is well known that physical activity is beneficial for people with positive results for physical status and mental wellbeing. However, physical exercise decrease the immune response and may induce a allergy anaphylaxis at some situation as follows. A common example is exercise-induced asthma, exercise-induced urticaria, exercise-induced anaphylaxis and FDEIAn (food-dependent exercise-induced allergy anaphylaxis). Generally, anaphylaxis is a severe, potentially fatal, hypersensitivity reaction of rapid onset. It is a dramatic clinical emergency. Actually, there are lots of etiologic factors of anaphylaxis, the principal immunologic triggers are foods, insect stings, and drugs. In recent, physical exercise is also related with the anaphylaxis. In this paper, we present the current views of physiological mechanisms underlying physical anaphylaxis within the context of exercise immunology. we also deals with a detailed 2 kinds of EIA (exercise-induced asthma, exercise-induced anaphylaxis) and exercise prescription and medical treatment for exercise-induced asthma, exercise-induced anaphylaxis and CU (chronic urticaria). METHODS: At first, we analyzed and presented the causes, symptoms, pathophysiology, testing, treatment and prescription of exercise-induced asthma, exercise-induced urticaria, exercise-induced anaphylaxis and FDEIAn through many experiments and references. RESULTS: Exercise-induced asthma is a typical asthmatic attack which follows a strenuous exercise lasting 5 to 10 minutes in circumstances of dry and cold air situation. Avoid of exercise in that conditions and drug treatment (beta-2 adrenergic agonists) must preferentially be preventive. Physical urticarias are a unique subgroup of CU in which patients develop urticaria secondary to environmental stimuli. Common triggers include cold and heat temperature, water, sunlight and even physical exercise. it is responsible for approximately 20-30% of all cases of chronic urticaria. FDEIAn is induced by different types and various intensities of physical exercise, and this is distinct from food allergy. It is useful to test both in vivo and in vitro an extensive panel of foods. Avoidance of allergenic foods for at least 4 h before exercise has prevented further episodes in all our patients with specific FDEIAn. CONCLUSIONS: It is concluded that anaphylaxis remains a continuous challenge for the diagnosis and treatment. The adequate management of anaphylaxis requires rapid diagnosis, implementation of primary and secondary prevention measures, and immediate administration of subcutaneous epinephrine. Furthermore, patient education is necessary to heighten awareness of the sign and symptoms of 2 kinds of EIA and FEDIAn.

Research Trends on Atopic Dermatitis an Autoimmune Disease and Exercise

“…최근 환경적 요인과 아토피피부염 관련 연구가 다양하게 진행되고 있으며, 강도차이에 의한 신체활동 및 여가활동에 서 아토피피부염의 호전여부에 상관관계관련 연구가 다각적으로 진행 되고 있다 [10]. 규칙적인 운동 시 면역반응에 영향을 미치는 것으로 알 려져 있으며, 특히 면역T세포의 증식 및 생성관련 사이토카인이 활성 화된다고 보고하고 있다 [11]. 또한, 신체활동에 따라 알레르기 반응, 다 양한 종류의 두드러기, 무기력, 천식, 혼수상태를 포함한 아나필락시스 (Anaphylaxis) 등이 일어나게 된다 [11].…”

“…규칙적인 운동 시 면역반응에 영향을 미치는 것으로 알 려져 있으며, 특히 면역T세포의 증식 및 생성관련 사이토카인이 활성 화된다고 보고하고 있다 [11]. 또한, 신체활동에 따라 알레르기 반응, 다 양한 종류의 두드러기, 무기력, 천식, 혼수상태를 포함한 아나필락시스 (Anaphylaxis) 등이 일어나게 된다 [11]. 특히, 아토피피부염 환자의 절반 정도가 재발을 경험하며, 일부 환자는 알레르기 비염, 천식 및 알레르 기를 동반하여 경험하게 된다 [12]…”