2022
DOI: 10.3389/fdmed.2022.1048137
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The scientific management of deep carious lesions in vital teeth using contemporary materials—a narrative review

Abstract: AimThe aim of this article is to review the scientific evidence for deep caries removal in permanent vital teeth and the choice of dentine replacement material and restoration of the teeth to maintain long term tooth vitality and function.MethodThe two position statements namely the European Society of Endodontology and the American Association of Endodontists position statements on vital pulp therapy will be scrutinized and compared with regards to the deep caries removal strategy and assessed for evidence of… Show more

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Cited by 4 publications
(2 citation statements)
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References 163 publications
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“…The development of a chairside diagnostic biomarker test with high specificity and sensitivity may assist in future clinical decision-making between VPT or RCT. Matrix Metalloproteinase-9 (MMP-9) has been of particular interest in recent studies as it is expressed in high concentrations in inflamed pulps as an indicator of tissue breakdown [93,94]. Mente et al [95] sampled pulpal blood after a partial pulpotomy in 44 teeth with deep caries and found that the MMP-9 levels were significantly higher in patients with moderate to severe pulpitis.…”
Section: Inflammation: Degree Of Bleeding Bleeding Time and Concentra...mentioning
confidence: 99%
“…The development of a chairside diagnostic biomarker test with high specificity and sensitivity may assist in future clinical decision-making between VPT or RCT. Matrix Metalloproteinase-9 (MMP-9) has been of particular interest in recent studies as it is expressed in high concentrations in inflamed pulps as an indicator of tissue breakdown [93,94]. Mente et al [95] sampled pulpal blood after a partial pulpotomy in 44 teeth with deep caries and found that the MMP-9 levels were significantly higher in patients with moderate to severe pulpitis.…”
Section: Inflammation: Degree Of Bleeding Bleeding Time and Concentra...mentioning
confidence: 99%
“…However, it is difficult to elicit accurate information on pulp symptoms in pediatric dentistry. Correctly diagnosing the pulp status of deep carious lesions in primary teeth is crucial for selecting the best vital pulp therapy [7,8]. Pulp sensibility and vitality tests measuring the nerve response rather than assessing the blood flow of the pulp have significant limitations [9].…”
Section: Introductionmentioning
confidence: 99%