Introduction. Chest pain (CP) diagnostics accuracy remains
debatable for both general practitioners (GP) or emergency department (ED)
physicians for patients in HEART score (HS) low- and intermediate-risk
groups which prompted us to review our electronic database for all patients
admitted via our center?s ED during 2014 to 2020 for CP and suspect acute
coronary syndrome. Methods. Patients were divided in function of low- or
intermediate-risk HS and assessed during a three month follow up for
angiogram results, MACE, lab results and echo parameters. Results. Of 585
patients included, low-risk HS group (21,4%, 36% were women) had significant
coronary disease on angiogram in 68%, while for intermediate-risk HS group
(78.6%, with 32.6% women) it was for 18.4% of patients (p < 0,0005). Area
under the ROC curve of HS in detecting patients with ischemic heart disease
as a cause of CP was 0.771 (95% CI:0.772-0.820) with best cut-off point HS
was calculated at 3.5. Sensitivity and specificity were 89.2% and 57.6%
respectively. Adjusting for sex, lab results and HS, AUROC curve of this
model was 0.828 (95% CI:0.786-0.869; p < 0,0005) with cut-off of 77.95.
Sensitivity and specificity were 84,9% and 68% respectively. In the
three-month follow-up post-discharge, there was a significant difference in
MACE between groups (low-vs. intermediate-risk HS was 3.4 vs. 16.7% p <
0.05). Conclusion. HS for our CP patients admitted via our ED by GP and ED
physicians? referral, provides a quick and reliable prediction of ischemic
heart disease and MACE.