The Second Special Issue on Code Biology — An overview

Hofmeyr, Jan-Hendrik S.

doi:10.1016/j.biosystems.2019.104050

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Biosemiotics and Code Biology1

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2023

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“…Many others have pursued the biosemiotic realities of subcellular life. [69,[159][160][161][162][163][164][165][166][167][168][169][170].…”

Section: Biosemiotics and Code Biologymentioning

confidence: 99%

Why is Abiogenesis Such a Tough Nut to Crack?

Abel

2023

Preprint

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The latest life-origin literature is reviewed, along with grouping and classification of the most enduring models of abiogenesis. New trends are identified in origin-of-life thought. Astrobiology continues to deal mostly with inorganic and very elementary organic reactions in extreme environments. Nonequilibrium thermodynamics has received a great deal of attention. Attempts have been made to relate Bejan’s Constructal Law to life and abiogenesis. RNA World preclusions only seem to have grown, while ribozyme/peptide models have expanded. The biosemiotic movement and code biology is gaining influence in refining a more complete description of life. Prof James Tour at Rice University in a fourteen-lecture series lists a number of synthetic biochemical hurtles remaining that still need to be overcome. But the need for some sort of informational recipe, instruction, steering and control now seems to be the most prominent area of focus and concern. Even a protometabolism needed active selection and controls rather than mere constraints or law. The latest literature still does not elucidate how protometabolism was orchestrated in an inanimate, pre-evolutionary environment.

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