2023
DOI: 10.1093/alcalc/agad002
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The Self-Rated Effects of Alcohol Are Related to Presystemic Metabolism of Alcohol

Abstract: Aims A high number of alcohol units required to feel a subjective effect of alcohol predicts future alcohol use disorders (AUDs). The subjective response to alcohol can be measured using the validated retrospective self-rated effects of alcohol (SRE) questionnaire. Few studies have investigated the specific relationship between SRE and blood alcohol concentration (BAC) in an experimental setting. Methods Twenty healthy young … Show more

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“…In liver cells, alcohol can be initially metabolized into acetaldehyde before being subsequently oxidized into acetate by acetaldehyde dehydrogenase [ 50 , 51 ]. Excessive alcohol consumption causes acetaldehyde and ROS accumulation, resulting in oxidative stress [ 52 , 53 ].…”
Section: Discussionmentioning
confidence: 99%
“…In liver cells, alcohol can be initially metabolized into acetaldehyde before being subsequently oxidized into acetate by acetaldehyde dehydrogenase [ 50 , 51 ]. Excessive alcohol consumption causes acetaldehyde and ROS accumulation, resulting in oxidative stress [ 52 , 53 ].…”
Section: Discussionmentioning
confidence: 99%