This chapter presents an evolving model of relational psychodynamic family psychotherapy that is strongly embedded in personality systematics and relational science. Early versions of this model have been previously published (Magnavita, 2000(Magnavita, , 2002. Psycho-dynamic psychotherapy has expanded in its domain of operation from primarily an intrapsychic-biological model, originated by Freud, to one that is embedded in the relational matrix and personality systematics . There are other earlier versions of psychodynamic and relational approaches that share many features of this model but are beyond the scope of this chapter to review (Magnavita, 2007). One such model representing a significant advance is Wachtel's (1977) "cyclical psychodynamic" model that initially integrated both psychodynamic and behavioral approaches and later was expanded to include a systemic component, further broadening its application and theoretical explanatory power.New ideas emerge and are differentiated from existing ones and then inexorably integrated and absorbed into the mainstream. This dialectic process has allowed the field of psychodynamics to evolve into a theoretical and clinical approach that maintains some of the more robust constructs of affective-defensive operations, the power of unconscious processing, and transference-schematic representational systems which guide interpersonal relationships. This has been shaped by a number of disciplines such as neuroscience, system theory, developmental psychopathology, attachment theory, and affective science. The advancements in system theory 1 (von Bertalanffy, 1969) and ecological theory (Bronfenbrenner, 1979) have enveloped psychodynamics in a new, unified theoretical approach that depicts interrelated domains that can account for the spectrum of psychopathological-dysfunctional adaptations at the individual, dyadic, triadic, and sociocultural level (Magnavita