The sensitivity and specificity of vaginal sonography in detecting endometrial abnormalities in women with postmenopausal bleeding

Wolman, Igal; Sagi, Joseph; Ginat, Shimon; Jaffa, Ariel J.; Har‐Toov, J.; Jedwab, Gideon

doi:10.1002/(sici)1097-0096(199602)24:2<79::aid-jcu5>3.0.co;2-h

Cited by 20 publications

(13 citation statements)

References 8 publications

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“…Another 30 articles were obtained from scanning the reference lists of known primary and review articles in our personal files. After reviewing the full manuscripts of 145 articles, 36 English (3–6,11,14, 33–62), seven German (63–69), four Italian (70–73), two French (74,75), two Chinese (76,77), two Bulgarian (78,79), one Spanish (80), one Polish (81), one Turkish (82), and one Dutch (83) article were selected for inclusion in the overview. There were six articles in which the two reviewers initially disagreed on eligibility but this was resolved easily by consensus.…”

Section: Resultsmentioning

confidence: 99%

Ultrasonographic endometrial thickness for diagnosing endometrial pathology in women with postmenopausal bleeding: a meta‐analysis

Gupta

Chien

Voit

et al. 2002

Acta Obstet Gynecol Scand

261

164

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Our aim was to determine the diagnostic accuracy of endometrial thickness measurement by pelvic ultrasonography for predicting endometrial carcinoma and disease (hyperplasia and/or carcinoma) during an investigation of postmenopausal bleeding. We performed a systematic quantitative review of the available published literature, which consisted of online searching the MEDLINE and EMBASE databases (1966-2000) coupled with scanning of bibliography of known primary and review articles. The selection of studies, assessment of study quality, and extraction of data were performed in duplicate under masked conditions. Included in the analyses were 57 studies with 9031 patients. Accuracy data were summarized using likelihood ratios for various cut-off levels of abnormal endometrial thickness. The commonest cut-offs were 4 mm (9 studies) and 5 mm (21 studies), measuring both endometrial layers. None of the nine studies using the < or = 4 mm cut-off level were of good quality. Only four studies (out of the 21) used the < or = 5 mm cut-off level, which employed the best-quality criteria. Using the pooled estimates from these four studies only, a positive test result raised the probability of carcinoma from 14.0% (95% CI 13.3-14.7) to 31.3% (95% CI 26.1-36.3), while a negative test reduced it to 2.5% (95% CI 0.9-6.4). In conclusion, ultrasound measurement of endometrial thickness alone, using the best-quality studies cannot be used to accurately rule. However, a negative result at < or = 5 mm cut-off level measuring both endometrial layers in the presence of endometrial pathology rules out endometrial pathology with good certainty.

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Section: Resultsmentioning

confidence: 99%

Ultrasonographic endometrial thickness for diagnosing endometrial pathology in women with postmenopausal bleeding: a meta‐analysis

Gupta

Chien

Voit

et al. 2002

Acta Obstet Gynecol Scand

261

164

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show abstract

“…Fast 70 % aller gynäkologischen Konsultationen bei peri-und postmenopausalen Frauen stehen im Zusammenhang mit Blutungsstörungen [5]. Die PMPB ist das wichtigste klinische Warnsignal für das Endometriumkarzinom [6] und ist bei etwa 80 % der Patientinnen mit einem Endometriumkarzinom das erste Symptom [7,8].…”

Section: Relevanz Des Themasunclassified

Abklärung von postmenopausalen Blutungen (PMPB)

2002

Schweiz Ärzteztg

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“…Aufbauend auf Evidence-based Medicine (EBM) sollen Leitlinien eine Hilfeleistung und Orientierung im Sinne einer Effizienzsteigerung von Diagnostik und Therapie an der individuellen Patientin und im Sinne der Vertrauensbildung in die ärztliche Entscheidung erbringen [1][2][3]. «Leitlinien» sind systematisch entwickelte Darstellungen und Empfehlungen mit dem Zweck, Arzt und Patientin bei der Entscheidung über zweckdienliche Massnahmen der Krankenversorgung (Prävention, Diagnostik, Therapie und Nachbehandlung) unter spezifischen klinischen Umständen zu unterstützen [4].…”

Section: Präambelunclassified

Abklärung von postmenopausalen Blutungen (PMPB)

2000

Schweiz Ärzteztg

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The sensitivity and specificity of vaginal sonography in detecting endometrial abnormalities in women with postmenopausal bleeding

Cited by 20 publications

References 8 publications

Ultrasonographic endometrial thickness for diagnosing endometrial pathology in women with postmenopausal bleeding: a meta‐analysis

Ultrasonographic endometrial thickness for diagnosing endometrial pathology in women with postmenopausal bleeding: a meta‐analysis

Abklärung von postmenopausalen Blutungen (PMPB)

Abklärung von postmenopausalen Blutungen (PMPB)

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