There is a worldwide interest in implementing collaborative robots (Cobots) to reduce work-related Musculoskeletal Disorders (WMSD) risk. While prior work in this field has recognized the importance of considering Ergonomics & Human Factors (E&HF) in the design phase, most works tend to highlight workstations’ improvements due to Human-Robot Collaboration (HRC). Based on a literature review, the current study summarises studies where E&HF was considered a requirement rather than an output. In this article, the authors are interested in understanding the existing studies focused on Cobots’ implementation with ergonomic requirements, and the methods applied to design safer collaborative workstations. This review was performed in four prominent publications databases: Scopus, Web of Science, Pubmed, and Google Scholar, searching for the keywords ‘Collaborative robots’ or ‘Cobots’ or ‘HRC’ and ‘Ergonomics’ or ‘Human factors’. Based on the inclusion criterion, 20 articles were reviewed, and the main conclusions of each are provided. Additionally, the focus was given to the segmentation between studies considering E&HF during the design phase of HRC systems and studies applying E&HF in real-time on HRC systems. The results demonstrate the novelty of this topic, especially of the real-time applications of ergonomics as a requirement. Globally, the results of the reviewed studies showed the potential of E&HF requirements integrated into HRC systems as a relevant input for reducing WMSD risk.