The Separation of Alanine Enatiomer Derivatives by the Proton‐Inhibition Method

Abstract

Better peak shapes and complete separation of amino-3,5-dinitro derivatives by (5)-yV-(2-naphthyl)alanine derived chiral stationary phase (CSP) is achieved by adding a trace amount of acetic acid in the mobile phase. This method provides an indication of its broad applicability on direct separation of a series of aminocontaining enantiomers on CSP. In addition, the reversed elution order was obtained on its enatiomeric CSP.