The Serum Protein Levels of Newborn African Infants

Serum Protein Pattern in African Neonates

“…Similar findings were reported by Sandor (1966) for Europeans, and the raised maternal cx-and Pglobulins were explained by the increase in serum lipids during pregnancy. This study supports Edozien's report of higher y-globulin in the neonate than in the mother, but not that of Stanier and Thompson (1954) who reported the reverse.…”

“…Stanier and Thompson (1954), using paper electrophoresis, compared the serum protein pattern in 14 African neonates in Uganda with that found in 10 white American neonates by Longsworth, Curtis, and Pembroke (1945) using chemical fractionation: the African neonate had lower albumin and 5-globulin levels than the whites in America, but the y-globulin levels were the same. Carr and Gelfand (1960) analysed cord blood samples from 54 African and 11 European babies born in Rhodesia, and reported that the proportions of the serum protein fractions in the two races were identical.…”

“…In Europeans, there is general agreement that the serum of the mother at term has less albumin and y-globulin, but much more xand p-globulins than her infant; but in Africans, the reports are contradictory. Stanier and Thompson (1954) reported that the African mother at term had a lower percentage of albumin, but a higher one of globulin, including y-globulin, than the neonate. On the other hand, Edozien (1961) reported that the maternal serum y-globulin level was lower than that of the neonate in both Africans and Europeans.…”

Electrophoretic Studies of Serum Protein Patterns in Newborn Indian Infants

“…But similar studies on African infants showed the serum gamma globulin of cord blood to be lower than that of the maternal blood at delivery (Stanier and Thompson, 1954). Our previous studies on plasma proteins in normal pregnant women at term showed a lower serum albumin level than that reported by foreign workers; however the serum gamma globulin in these women was much higher (Coryell, Beach, Robinson, Macy and Mack, 1950;Mack, Robinson, Wiseman, Schoeb and Macy, 1951;Brown, 1954; Purandare, Satoskar and Lewis, 1954).…”

Gamma Globulin Levels in Several Populations

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Several studies utilizing different methods of measurement indicate that the serum gamma globulin levels of geographically separated populations may differ considerably [4,10,12,13,15]. The recent discovery of inherited qualitative differences in the serum gamma globulins (Gm groups) [9] has focused attention on the possible re lationship between quantitative variations and genetic factors.

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