Horizontal or highly deviated wells with long completions that are open to flow are used to increase the contact between the well and the hydrocarbon-bearing reservoir (Joshi, 1991). However, these wells can suffer from non-uniform inflow rates along the open completion, which results in early breakthrough of unwanted fluid phases such as gas or water. This is due to: (1) the so-called 'heel-toe' effect (Birchenko et al., 2010; Dilib and Jackson, 2013), caused when a significant frictional pressure drop occurs along the production tubing, leading to a lower tubing pressure and, therefore, a larger reservoir pressure drawdown at the heel of the well as compared to the toe, and (2) permeability variations along the well caused by reservoir heterogeneity (Dilib et al., 2012; Dilib and Jackson, 2013). The exact pattern of this permeability heterogeneity around any given well is generally uncertain.