The short-term outcome of severe blunt head injury as reported by relatives of the injured persons.

McKinlay, William W.; Brooks, D N; Bond, Michael R.; Martinage, D P; Marshall, M M

doi:10.1136/jnnp.44.6.527

Cited by 404 publications

(181 citation statements)

References 10 publications

(6 reference statements)

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“…Among the survivors, 80,000 to 90,000 individuals are left with significant long-term cognitive and motor disabilities (Jacobs, 1988;Max, Rice, & MacKenzie, 1990;McKinlay, Brooks, Bond, Martinage, & Marshall, 1981;Rutland-Brown, Langlois, Thomas, & Xi, 2006;Thomsen, 1984;Thurman, Alverson, Dunn, Guerrero, & Sniezek, 1999). However, efforts to identify the neuropathologic correlates of these deficits have gained only limited success to date (Bigler, 2001a;Levine et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

Structural consequences of diffuse traumatic brain injury: A large deformation tensor-based morphometry study

et al. 2008

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Traumatic brain injury (TBI) is one of the most common causes of long-term disability. Despite the importance of identifying neuropathology in individuals with chronic TBI, methodological challenges posed at the stage of inter-subject image registration have hampered previous voxel-based MRI studies from providing a clear pattern of structural atrophy after TBI. We used a novel symmetric diffeomorphic image normalization method to conduct a tensor-based morphometry (TBM) study of TBI. The key advantage of this method is that it simultaneously estimates an optimal template brain and topology preserving deformations between this template and individual subject brains. Detailed patterns of atrophies are then revealed by statistically contrasting control and subject deformations to the template space. Participants were 29 survivors of TBI and 20 control subjects who were matched in terms of age, gender, education, and ethnicity. Localized volume losses were found most prominently in white matter regions and the subcortical nuclei including the thalamus, the midbrain, the corpus callosum, the mid-and posterior cingulate cortices, and the caudate. Significant voxel-wise volume loss clusters were also detected in the cerebellum and the frontal/ temporal neocortices. Volume enlargements were identified largely in ventricular regions. A similar pattern of results was observed in a subgroup analysis where we restricted our analysis to the 17 TBI participants who had no macroscopic focal lesions (total lesion volume> 1.5 cm 3 ). The current study confirms, extends, and partly challenges previous structural MRI studies in chronic TBI. By demonstrating that a large deformation image registration technique can be successfully combined with TBM to identify TBI-induced diffuse structural changes with greater precision, our approach is expected to increase the sensitivity of future studies examining brain-behavior relationships in the TBI population.

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Section: Introductionmentioning

confidence: 99%

Structural consequences of diffuse traumatic brain injury: A large deformation tensor-based morphometry study

et al. 2008

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“…A. Livingston et al, 2010b;Manskow et al, 2015;McKinlay et al, 1981;Norup et al, 2010;Norup et al, 2012;Oddy et al, 1978). When the caregiver or close family member experiences lower burden, less anxiety and a good health, this has a positive impact on the person with severe TBI (O'Neill & Carter, 1998).…”

Section: Introductionmentioning

confidence: 99%

Patterns of change and stability in caregiver burden and life satisfaction from 1 to 2 years after severe traumatic brain injury: A Norwegian longitudinal study

Manskow

Friborg

Røe

et al. 2017

NRE

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OBJECTIVE:To assess burden and life satisfaction in family members of patients with severe traumatic brain injury (sTBI) at 1 and 2 years post-injury, examine if change in burden can be predicted by family member and patient demographics, patient's functional status, family members social network or level of burden at 1 year. METHODS:Prospective national multicenter study. Self-report from family members, patient data collected from a national cohort study on patients with sTBI. 80 family members participated. MAIN OUTCOME MEASURE:The Caregiver Burden Scale (CBS), life satisfaction. RESULTS:Total burden increased between years 1 and 2 post-injury (P=0.04). Thirty percent of the family members reported an increased burden, 55% were stable, and 15% had a decrease in burden between the two follow-up times. Logistic regression analyses revealed that experiencing loneliness was an independent predictor of increased burden from 1 to 2 years post-injury (OR=4.35, P<0.05). Life Satisfaction was lower at the 2 year follow-up than at 1 year (p=0.03). CONCLUSIONS:The results demonstrate a need for long-term follow-up of patients and family members that focuses on professional support to relieve burden and risk of loneliness or social isolation. This group may benefit from additional follow-up interventions tailored to their needs.

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“…Les auteurs rapportent des niveaux de dépression (Douglas & Spellacy;Gillen et al, 1998;Hawley et al, 2003;Kreutzer et al, 1994a;Livingston, 1987;Ponsford, Olver, Ponsford, & Nelms, 2003;Marsh, Kersel, Havill, & Sleight, 1998a;Marsh et al, 2002;Turner et al, 2007;) et d'anxiété cliniquement significatifs (Hawley et al, 2003;Kreutzer et al, 1994a;Livingston, 1987;Marsh et al, 1998a;Marsh et al, 2002;Ponsford et al, 2003). Ces états psychopathologiques et le stress chez l'aidant sont particulièrement sévères durant la première année suivant le TCC (Gillen et al, 1998;Livingston et al, 1985;Marsh et al, 1998a;Marsh et al, 2002;McKinlay, Brooks, Bond, Martinage, & Marshall, 1981). Des auteurs estiment l'incidence de la dépression à plus de 60 % chez les aidants (Douglas & Spellacy, 2000).…”

Section: Les Impacts Comportementaux Et Psychopathologiques Directs Ounclassified

“…Elle peut également consister en un amalgame de symptômes cognitifs, comportementaux, émotionnels et psychophysiologiques (Dohrenwend, Shrout, Egri & Mendelsohn, 1980 Les modifications se produisant au niveau de la personnalité (Brooks et al, 1986;Gillen et al, 1998;Herbert, 2007;Knight et al, 1998;Kreutzer et al, 1994a;McKinlay et al, 1981), de l'humeur (Ergh et al, 2002;Gillen et al, 1998;Groom, Shaw, O'Connor, Howard, & Pickens, 1998;Kreutzer et al, 1994a;Knight et al, 1998;Livingston et al, 2010;Marsh et al, 1998a;Marsh et al, 2002;McKinlay et al, 1981;McPherson, Pentland, & McNaughton, 2000;Sander 2007) et du comportement chez la victime (Ergh et al, 2002;Gillen et al, 1998;Groom et al, 1998;Harris, Godfrey, Partridge & Knight, 2001;Riley, 2007) causeraient une détresse psychologique chez l'aidant. Les états pathologiques chez la victime de TCC ont un impact sur la satisfaction de l'aidant à l'égard de la vie (Wells, Dywan & Dumas, 2005) et accentuent le fardeau que doit porter l'aidant (Sander, 2007).…”

Section: Les Impacts Comportementaux Et Psychopathologiques Directs Ounclassified

Effet de la détresse psychologique du proche aidant sur le fonctionnement exécutif de la personne ayant subi un traumatisme crânio-cérébral /

Larouche¹

2012

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Enfin, l'analyse des résultats suggère que la détresse psychologique de l'aidant et de la victime de TCC pourrait agir tel un double effet sur le fonctionnement cognitif exécutif de la victime de TCC : la détresse psychologique de l'aidant, aurait un effet sur la IV détresse psychologique de l'individu cérébrolésé et vice-versa. Ensemble, la détresse psychologique de l'aidant et de la victime de TCC aurait un effet potentiel sur certains aspects du fonctionnement exécutif de la victime de traumatisme crânien. Table des matièresSommaire ii

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The short-term outcome of severe blunt head injury as reported by relatives of the injured persons.

Cited by 404 publications

References 10 publications

Structural consequences of diffuse traumatic brain injury: A large deformation tensor-based morphometry study

Structural consequences of diffuse traumatic brain injury: A large deformation tensor-based morphometry study

Patterns of change and stability in caregiver burden and life satisfaction from 1 to 2 years after severe traumatic brain injury: A Norwegian longitudinal study

Effet de la détresse psychologique du proche aidant sur le fonctionnement exécutif de la personne ayant subi un traumatisme crânio-cérébral /

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