The sick motoneurone hypothesis of muscular dystrophy

Being the smallest functional units under neural control, motor units play an integral role in muscle physiology. However, at the present time, there does not exist any widely accepted technique for quantifying or estimating the number of motor units in a muscle. Specifically, the existing techniques are the increment-counting technique, a technique based on spike-triggered averaging, and a macro-EMG based technique which vary in invasiveness from noninvasive to highly invasive, respectively. We discuss each of these techniques, along with their associated shortcomings, in detail.

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A review of techniques employed to estimate the number of motor units in a muscle

Slawnych

Laszlo

Hershler

1990

Muscle and Nerve

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Implications of increased S100β and Tau5 proteins in dystrophic nerves of two mdx mouse models for Duchenne muscular dystrophy

Krishnan

Aartsma‐Rus

Overzier

et al. 2020

Molecular and Cellular Neuroscience

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Age, diet and injury affect the survival of facial motoneurons

et al. 2003

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The sick motoneurone hypothesis of muscular dystrophy

Cited by 4 publications

References 147 publications

A review of techniques employed to estimate the number of motor units in a muscle

A review of techniques employed to estimate the number of motor units in a muscle

Implications of increased S100β and Tau5 proteins in dystrophic nerves of two mdx mouse models for Duchenne muscular dystrophy

Age, diet and injury affect the survival of facial motoneurons

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