2023
DOI: 10.21608/bmfj.2023.203221.1795
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The Significance of Expression of MUC 4 and IMP-3 in Benign Prostatic Hyperplasia, High Grade Prostatic Intraepithelial Neoplasia and Prostatic Adenocarcinoma(immunohistochemical study)

Zeinab Elshawarby,
kareem El Attar,
naglaa shalan

Abstract: Background: Prostate cancer is one of the most frequent malignancies worldwide. Mucin 4(MUC4) is a transmembrane mucin that is contributed in cell signaling events that guide the proliferation of cells. Insulin-like growth factor 2 (IGF2) messenger RNA binding protein 3 (IMP3) has been linked to tumorgenesis and progression of many cancers. Aim: This study aimed to evaluate MUC4 and IMP-3 expression in different prostatic lesions and to relate the results with clinicopathological data. Material and method: Thi… Show more

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