1963
DOI: 10.1016/0002-8703(63)90375-2
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The significance of late systolic murmurs

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Cited by 373 publications
(70 citation statements)
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“…Since Barlow's description, 13) a variety of names have been given to mitral valve prolapse, including the click-murmur syndrome, the floppy mitral valve syndrome, myxomatous mitral valve, and idiopathic mitral valve prolapse. Although most cases appear to be sporadic, echocardiographic screening of families for MVP has suggested autosomal dominant inheritance of the trait with an age and sex dependent expression.…”
Section: Discussionmentioning
confidence: 99%
“…Since Barlow's description, 13) a variety of names have been given to mitral valve prolapse, including the click-murmur syndrome, the floppy mitral valve syndrome, myxomatous mitral valve, and idiopathic mitral valve prolapse. Although most cases appear to be sporadic, echocardiographic screening of families for MVP has suggested autosomal dominant inheritance of the trait with an age and sex dependent expression.…”
Section: Discussionmentioning
confidence: 99%
“…Now that the association between these two syndromes is fairly well established, one wonders if the initial studies of these two syndromes were actually partial descriptions of only one syndrome! Perhaps Reid (1961) and Barlow (1965) concentrated much on the origin of the auscultatory abnormalities of MVP syndrome and thereby failed to pay attention to the coexisting skeletal abnormalities (straight back, scoliosis, and pectus) which are now considered important nonauscultatory clinical features of the MVP syndrome (Bon et al, 1975;Solomen er al., 1975). Similarly, could Rawlings have focused more on the skeletal abnormalities, and thereby failed to note the auscultatory features of MVP syndrome as we know it today?…”
Section: One Complex or Two Different Syndromes?mentioning
confidence: 99%
“…In-two patients it is possible that digoxin was responsible for the cardiographic abnormality. 11, Ill, aVL B) Exercise ECG. The mean duration of exercise was 6.6 minutes (7.6 for men and 4.9 minutes for women).…”
Section: Electrocardiographymentioning
confidence: 99%