The Significance of Platelet Count in Short-Term Prognosis of Type B Acute Aortic Dissection Patients

Abstract

Background: The lower number of platelet (PLT) has been found to be a risk factor in patients with type A acute aortic dissection (AAD) In admission. However prognostic implications of the PLT count in the type B AAD patients has not yet been elucidated. Methods: We consecutively enrolled 81 patients which confirmed with type B. Patients were divided into survival group and death group and PLT count were measured on admission. Univariate analysis and multiple logistic regression analysis were used to identify the predictors of in-hospital mortality. Results: Compared with the survival group, the death group PLT count was significant lower (172.07±57.38×10 9 /L vs. 227.13±75.97×10 9 /L, P<0.05). The results showed PLT count (HR: 0.993, 95% CI: 0.987-0.997, P=0.043), the area under the ROC curve of PLT count was 0.717, the best cut off was 179.5 × 10 9 / L, the sensitivity was 72.5%, the specificity was 63.3%, P=0.001; Log Rang test results showed that there was a statistically significant difference in cumulative survival between the high PLT count group (>179.5 × 10 9 / L) and the low PLT count group (<179.5 × 10 9 / L) (P=0.001). Conclusions: Low PLT on admission count is one of the specific dead risk factors for type B AAD in-hospital patients.