Peptic ulcer perforation is a frequent emergency, which must be resolved on time. It is closely related to Helicobacter pylori infection, smoking and the consumption of NSAIDs. The aim was to determine the surgical management and the description of the intraoperative findings in patients admitted with the diagnosis of perforated peptic ulcer in the General Surgery Service of the University Hospital of Maracaibo. The clinical history of 42 patients diagnosed with Perforated Peptic Ulcer, admitted in the General Surgery service of the University Hospital of Maracaibo in a period from January 2016 to June 2019, was reviewed. The average age of onset was 44.88 ± 6.04 years. 88.09% of the patients belonged to the male sex. On the other hand, the most frequent location of the ulcer corresponded to those of grade III, according to the classification of peptic ulcers described by Johnson. The techniques implemented for the closure correspond to, simple closure in 5 (11.90%), ulcorraphy + Graham patch omentopexy in 29 (69.04%) and Heineke-Mikulicz pyloroplasty in 8 (19.04%) cases. Mortality was located at 16.66% associated with sepsis. It was concluded that the management of the perforated peptic ulcer was carried out mainly by ulcorraphy + Graham patch omentopexy, then by pyloroplasty, and lastly by simple ulcer closure.