Abstract:The occurrence of atrial fibrillation (AF), one of the most common and socially significant arrhythmias, is associated with the presence of fibrosis sites. Fibrosis is the presence of non-conductive fibroblast cells, separating cardiomyocytes and introducing heterogeneity into the conducting atrial tissue. Thus fibrosis may be a substrate of spiral-wave reentry, provoking the occurrence of AF and is often associated with its persistent form. In this work, we propose for the first time a fundamentally new appro… Show more
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