The size of fat tail does not have an effect on growth performance and carcass characteristics in Lori-Bakhtiari lambs

Khaldari, Majid; Azarfar, Arash; Pahlavan, R.

doi:10.1016/j.smallrumres.2020.106088

Cited by 8 publications

(6 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Currently, fat tail is not conducive to breeding programs (Li et al, 2018; Moradi et al, 2012; Zhu et al, 2021), because: (1) most of the fat is deposited in the tail, leading to decreased carcass and intermuscular fat deposits, which affects carcass percentage and meat quality (Alizadeh et al, 2013; Khaldari et al, 2007; Yousefi et al, 2012); (2) more feed is needed for fat deposition than for meat production (Sillence, 2004); and (3) large fat tail is a critical obstacle for ram fertility. However, it has been reported the size of fat tail does not have an effect on growth rate in sheep (Khaldari et al, 2020). Marker‐assisted selection for improvement of economic traits in livestock is a powerful and effective method, as more founder alleles were represented among the favorable QTL alleles (Pedersen et al, 2009).…”

Section: Genetic Parameters Of Growth Carcass Composition and Meat Qu...mentioning

confidence: 98%

“…(3) large fat tail is a critical obstacle for ram fertility. However, it has been reported the size of fat tail does not have an effect on growth rate in sheep (Khaldari et al, 2020). Marker-assisted selection for improvement of economic traits in livestock is a powerful and effective method, as more founder alleles were represented among the favorable QTL alleles (Pedersen et al, 2009).…”

Section: Gen Et Ic Pa R a M Et Er S Of Grow T H Ca Rca S S Com Posi ...mentioning

confidence: 99%

See 1 more Smart Citation

Genetic basis of muscle‐related traits in sheep: A review

et al. 2022

View full text Add to dashboard Cite

Sheep is a major contributor to global food production among livestock and one of the great sources of red meat for human consumption. Several QTL and numerous genes with major and minor effects have been identified in association with the muscle characteristics in sheep breeds worldwide. Understanding the genetic background of growth and carcass-related traits in sheep is a major factor in increasing muscle growth, muscle hypertrophy and, eventually, meat production. This review concisely shows how major signaling pathways control skeletal muscle growth. Herein we aimed to discuss and summarize different research findings on genomic regions related to carcass traits and meat production in sheep. Several causative mutations with major effects on different muscle-related traits have been reported in various sheep breeds. A general overview of the studies on main candidate genes showed that some alleles have major phenotypic effects in different breeds with commercial and farm level usability. However, numerous genes with minor effects were also reported regarding the polygenic nature of muscle-related traits. The knowledge of the candidate genes involved in growth traits and their effects provides valuable information for breeding and selection of muscularity traits.

show abstract

Section: Genetic Parameters Of Growth Carcass Composition and Meat Qu...mentioning

confidence: 98%

Section: Gen Et Ic Pa R a M Et Er S Of Grow T H Ca Rca S S Com Posi ...mentioning

confidence: 99%

Genetic basis of muscle‐related traits in sheep: A review

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Fat tailed breeds comprise approximately 25% of the world sheep population [ 3 ] and are grazed in a wide range of countries. The major biological role of the fat tail is to serve as an energy store against periodic food scarcity, such as in drought and winter [ 4 ]. It has also been used as a source of fat (or ghee) for human consumption for millennia [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

“…Historically, the climatic conditions in these areas, as well as the nutritional and religious food requirements of the people, encouraged sheep producers to select for higher fat tail weight [ 6 ]. Although fat-tailed sheep breeds are still preferred under local pastoral, desert, or semi-desert conditions in several societies [ 7 ], most of the advantages of a large fat tail have recently reduced in importance due to the improved forage availability and decreased price for the product, especially in genetic improvement programs [ 4 , 8 ].…”

Section: Introductionmentioning

confidence: 99%

Hitchhiking Mapping of Candidate Regions Associated with Fat Deposition in Iranian Thin and Fat Tail Sheep Breeds Suggests New Insights into Molecular Aspects of Fat Tail Selection

Moradi

Nejati‐Javaremi

Moradi-Shahrbabak

et al. 2022

Animals

View full text Add to dashboard Cite

The fat tail is a phenotype that divides indigenous Iranian sheep genetic resources into two major groups. The objective of the present study is to refine the map location of candidate regions associated with fat deposition, obtained via two separate whole genome scans contrasting thin and fat tail breeds, and to determine the nature of the selection occurring in these regions using a hitchhiking approach. Zel (thin tail) and Lori-Bakhtiari (fat tail) breed samples that had previously been run on the Illumina Ovine 50 k BeadChip, were genotyped with a denser set of SNPs in the three candidate regions using a Sequenom Mass ARRAY platform. Statistical tests were then performed using different and complementary methods based on either site frequency (FST and Median homozygosity) or haplotype (iHS and XP-EHH). The results from candidate regions on chromosome 5 and X revealed clear evidence of selection with the derived haplotypes that was consistent with selection to near fixation for the haplotypes affecting fat tail size in the fat tail breed. An analysis of the candidate region on chromosome 7 indicated that selection differentiated the beneficial alleles between breeds and homozygosity has increased in the thin tail breed which also had the ancestral haplotype. These results enabled us to confirm the signature of selection in these regions and refine the critical intervals from 113 kb, 201 kb, and 2831 kb to 28 kb, 142 kb, and 1006 kb on chromosome 5, 7, and X respectively. These regions contain several genes associated with fat metabolism or developmental processes consisting of TCF7 and PPP2CA (OAR5), PTGDR and NID2 (OAR7), AR, EBP, CACNA1F, HSD17B10,SLC35A2, BMP15, WDR13, and RBM3 (OAR X), and each of which could potentially be the actual target of selection. The study of core haplotypes alleles in our regions of interest also supported the hypothesis that the first domesticated sheep were thin tailed, and that fat tail animals were developed later. Overall, our results provide a comprehensive assessment of how and where selection has affected the patterns of variation in candidate regions associated with fat deposition in thin and fat tail sheep breeds.

show abstract

“…Approximately 25% of the world sheep population comprises fat tail breeds that are grazed in a wide region of countries especially in Asia and northern parts of Africa. The fat tail is considered as an adaptive response of animal to a hazardous environment and is a valuable energy resource for the animal during migration and winter (Khaldari et al, 2020). Sheep production constitutes the most important component of the Iranian livestock industry whit a total of approximately 50 million head.…”

Section: Introductionmentioning

confidence: 99%

Association of Palm gene mutations with structure and function of paralemmin proteins in Lori-Bakhtiari and Zel sheep Breeds

Zare

Sadeghi

Ahmadpanah

et al. 2022

Acta Sci. Anim. Sci.

View full text Add to dashboard Cite

The aim of current study was to survey genetic variability of PALM gene’s exon 3 and 4 by PCR-SSCP and DNA sequencing in Zel and Lori Bakhtiari sheep breeds. The SIFT (Sorting Intolerant from Tolerant) and PHyre2 program were used to predict the possible impact of amino acid substitutions on performance and structure of the paralemmin protein. A total of 140 animal's from 2 Iranian sheep breeds with different fat metabolisms, Lori-Bakhtiari and Zel sheep breeds were considered. The results showed that there are two polymorphic sites including a nonsynonymous substitution and an insertion mutation (49bp). Non-synonymous mutation deduced Thr20Ala amino acid exchange and ensuing two different structures for paralemmin protein that could be potentially affect protein structure and function during the interaction with glutamate in the cytosolic surface of plasma membrane. PALM gene, according to evolutionary path, is classified into two separate categories. In first covey, Gallus gallus and in second one, other species in several branches, so that the sequence of cow and sheep is placed in a sub-branch which forms a clade beside goat. Comparison of illustrated coding region sequences, PALM gene among different species, is of orthologous which are derived from a common ancestor.

show abstract

The size of fat tail does not have an effect on growth performance and carcass characteristics in Lori-Bakhtiari lambs

Cited by 8 publications

References 31 publications

Genetic basis of muscle‐related traits in sheep: A review

Genetic basis of muscle‐related traits in sheep: A review

Hitchhiking Mapping of Candidate Regions Associated with Fat Deposition in Iranian Thin and Fat Tail Sheep Breeds Suggests New Insights into Molecular Aspects of Fat Tail Selection

Association of Palm gene mutations with structure and function of paralemmin proteins in Lori-Bakhtiari and Zel sheep Breeds

Contact Info

Product

Resources

About