The SKT—A Short Cognitive Performance Test for Assessing Deficits of Memory and Attention

Lehfeld, Hartmut; Erzigkeit, H.

doi:10.1017/s104161029700478x

Cited by 72 publications

(48 citation statements)

References 10 publications

(12 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The neuropsychological evaluation was based on the SKT [18], a cognitive performance test including nine subtests for assessing deficits of memory and attention. The published reliability data vary between 0.86 and 0.88 [18].…”

Section: Methodsmentioning

confidence: 99%

A Biopsychosocial Model of Interferon-Alpha-Induced Depression in Patients with Chronic Hepatitis C Infection

Baranyi¹,

Meinitzer²,

Stepan³

et al. 2013

Psychother Psychosom

View full text Add to dashboard Cite

Background: The aim of this prospective study was to gain a more comprehensive picture of the biopsychosocial effects of interferon-α (IFN-α) treatment of patients with chronic hepatitis C (HCV). The predictors of depressive development and changes in health-related quality of life, life satisfaction and cognitive ability were measured with the inclusion of the social context. Furthermore, the effects of IFN-α treatment on indoleamine 2,3-dioxygenase, the level of tryptophan supply in the brain, the development of neurotoxic kynurenine metabolites and the thyroid glands were investigated. Therefore, for the first time the conditions for the development of depressive episodes in HCV patients treated with IFN-α were examined over the entire period of treatment as well as 3 months later, applying a holistic biopsychosocial model. Method: Psychiatric and biological assessments were carried out at 6 different times: before, during (at 1, 3, 6 and 9 months) and after the end of IFN-α treatment. Results: During IFN-α treatment 22 (53.7%) of 41 patients fulfilled the criteria for a treatment-related depressive disorder at least once during treatment. Contributing factors are tryptophan depletion (tryptophan to competing amino acids quotient), increased neurotoxic challenge (kynurenine to kynurenic acid quotient), less social support, female gender, preexisting psychiatric vulnerability, means of transmission, low financial security, impaired sexual satisfaction, small circle of friends, impaired physical role, strong body pain, low general health and vitality, reduced social functioning, impaired mental health and impaired emotional role. Conclusions: The awareness of relevant risk factors of IFN-α treatment-induced depression is essential to develop preventative treatment strategies.

show abstract

Section: Methodsmentioning

confidence: 99%

A Biopsychosocial Model of Interferon-Alpha-Induced Depression in Patients with Chronic Hepatitis C Infection

Baranyi¹,

Meinitzer²,

Stepan³

et al. 2013

Psychother Psychosom

View full text Add to dashboard Cite

show abstract

“…In the follow-up after discharge from the hospital, a battery of tests was used which consisted of the syndrome short test (Syndrom-Kurztest, SKT) [29,30] , the MMSE, a verbal fl uency test (the number of animals named within 60 s) and a clock drawing test in the version of Manos and Wu [31] .…”

Section: Assessment Proceduresmentioning

confidence: 99%

Prevalence and Persistence of Mild Cognitive Impairment among Elderly Patients in General Hospitals

Bickel

Mösch

Seigerschmidt

et al. 2006

Dement Geriatr Cogn Disord

View full text Add to dashboard Cite

The aim of the present study was to determine the prevalence of mild cognitive impairment (MCI) in elderly patients in general hospitals and to investigate the persistence of the cognitive deficits after discharge from the hospital. In a sample consisting of 794 non-demented patients in general hospitals aged 65–85 years, we found an MCI prevalence of 36.1%. The positive predictive value for cognitive impairment 3.5 months after hospital discharge was 61.0%. The deficits in multiple-domain MCI proved to be particularly stable with a positive predictive value of 82.9%. Elderly patients in general hospitals represent a high-risk group for MCI. These results indicate that general hospitals offer an opportunity for the early detection of incipient dementia.

show abstract

“…Norm values range from 0 to 27, and differentiate between profound (24-27), severe (19)(20)(21)(22)(23), moderate (14)(15)(16)(17)(18), mild (9-13), questionable (5-8) cognitive impairments, and no cognitive deficits (0-4). Published reliability data varied between 0.86 and 0.88 [32]. The German version of the 17-item Hamilton rating scale for depression (HAMD 17 ) was used to measure the severity of depressive symptomatology [33,34].…”

Section: Psychometric Testsmentioning

confidence: 99%

Psychiatric and Psychosocial Outcome of Orthotopic Liver Transplantation

Rothenhäusler¹,

Ehrentraut²,

Kapfhammer³

et al. 2002

Psychother Psychosom

View full text Add to dashboard Cite

Background:The study aimed to explore the prevalence of psychiatric disorders among orthotopic liver transplantation (OLT) recipients, and to investigate how psychiatric morbidity was linked to health-related quality of life (HRQOL). Methods: We recruited 75 patients who had undergone OLT a median of 3.8 years previously (range = 5-129 months). Psychiatric morbidity was assessed using the Structural Clinical Interview for the DSM-III-R. Psychometric observer-rating and self-rating scales were administered to evaluate cognitive functioning (SKT), depressive symptomatology (HAMD 17 ), posttraumatic stress symptoms (PTSS-10), social support (SSS), and HRQOL (SF-36 Health Status Questionnaire). Treatment characteristics were obtained from medical records. Results: 22.7% (n = 17) of our sample had a current or probable psychiatric diagnosis according to DSM-III-R: 2.7% full posttraumatic stress disorder (PTSD) (n = 2), 2.7% major depressive disorder (MDD) comorbid to full PTSD (n = 2), 1.3% MDD comorbid to partial PTSD (n = 1), and 16% partial PTSD (n = 12). Patients with PTSD symptoms demonstrated lower cognitive performance, higher severity of depressive symptoms and more unfavorable perception of social support. OLT-related PTSD symptomatology was associated with maximal decrements in HRQOL. The duration of intensive care treatment, the number of medical complications, and the occurrence of acute rejection were positively correlated with the risk of PTSD symptoms subsequent to OLT. Conclusion: OLT-related PTSD symptomatology impairing HRQOL is a complication for a subgroup of OLT recipients. Health-care providers should be aware of the possible presence of PTSD in OLT survivors.

show abstract

The SKT—A Short Cognitive Performance Test for Assessing Deficits of Memory and Attention

Cited by 72 publications

References 10 publications

A Biopsychosocial Model of Interferon-Alpha-Induced Depression in Patients with Chronic Hepatitis C Infection

A Biopsychosocial Model of Interferon-Alpha-Induced Depression in Patients with Chronic Hepatitis C Infection

Prevalence and Persistence of Mild Cognitive Impairment among Elderly Patients in General Hospitals

Psychiatric and Psychosocial Outcome of Orthotopic Liver Transplantation

Contact Info

Product

Resources

About