Using the theory of perverse sheaves of vanishing cycles, we define a homological invariant of knots in three‐manifolds, similar to the three‐manifold invariant constructed by Abouzaid and the second author. We use spaces of SL(2,C) flat connections with fixed holonomy around the meridian of the knot. Thus, our invariant is a sheaf‐theoretic SL(2,C) analogue of the singular knot instanton homology of Kronheimer and Mrowka. We prove that for two‐bridge and torus knots, the SL(2,C) invariant is determined by the l‐degree of the trueÂ‐polynomial. However, this is not true in general, as can be shown by considering connected sums of knots.