“…Bisegger et al 2005 reported gender differences as potential causes of greater vulnerability of teen girls for decreased HRQOL aspects than boys, from the age of 13 years on, besides being diabetic, such as the more drastic puberty for girls; the onset of menstruation, hormonal fluctuations (Toffol et al 2014;Tanna et al 2016), higher levels of perceived stress, and stress-related health complaints in adolescent girls than boys (Östberg et al 2015), with handling problems and difficulties in different ways, namely girls tend to direct their coping patterns inwards, and boys outwards (Wiklund et al 2012); and less body image satisfaction (Griffiths et al 2017) and self-esteem (Gouveia et al 2014), more sensitivity, empathic concern (Van der Graaff et al 2014), and argument due to the social demands placed on girls, that are more staggering and more difficult to achieve (Barcellos et al 2014). The difference in relationships with peers and social relations between girls and boys at the teenage (Rose and Asher 2017) is also that boys often have more privileges and are given more space than girls (Chawla 2004). Besides that, diabetic females trend to have worse metabolic control, higher frequency of microvascular complications, higher incidence of diabetic ketoacidosis (DKA), dyslipidemia, and weight problems than boys at adolescence (Forsander et al 2017).…”