The somatosensory evoked potentials of normal infants: Influence of filter bandpass, arousal state and number of stimuli

Multimodal neurophysiological monitoring in healthy infants born at term: normative continuous somatosensory evoked potentials data

“…During the VEEG recording, the trend‐SEP‐C calculates the latencies and the amplitude values of SEP components and the analysis allows combination of these values with behavioural states related to the EEG period. This is important because it has been demonstrated that SEPs are severely affected by the state of brain activity . We found that latencies and amplitudes of cortical SEPs (N1 component and complex N1‐P1) have lower values during AS and quiet‐wakefulness phases than in the QS phase.…”

“…We used a stimulation frequency (1.1Hz) lower than that commonly used in adults because it is more appropriate to the immaturity of the newborn infant's nervous system . SEP‐C measurements were performed in agreement with Bongers‐Schokking et al, who advocate that SEP recording in newborn infants should involve use of a band‐pass filter of 1–100Hz with a low number of stimuli (25–50), paying close attention to the behavioural state of the infant.…”

“…We used a stimulation frequency (1.1Hz) lower than that commonly used in adults because it is more appropriate to the immaturity of the newborn infant's nervous system . SEP‐C measurements were performed in agreement with Bongers‐Schokking et al, who advocate that SEP recording in newborn infants should involve use of a band‐pass filter of 1–100Hz with a low number of stimuli (25–50), paying close attention to the behavioural state of the infant. They demonstrated that a wide band‐pass filter (>100Hz) induces unacceptable distortion of the scalp potentials and signal artefacts, while the application of less than 50 stimuli is sufficient to obtain a cortical response but prevents system exhaustion .…”

“…The stimulus duration was 200 μ s, and intensity (10–20 mA) was regulated to produce a small thumb twitch (motor threshold intensity). The individual traces were the average of 50 measurements, analysis time was 200 ms, and the filter band‐pass was 1–100 Hz . Responses were recorded from cortical and cervical levels using the same electrode as VEEG and the reference electrode at Fz (C3’‐Fz, C3’‐C4’, C4’‐Fz, C4’‐C3’, and Cv7‐Fz).…”

Somatosensory Evoked Potentials in Very Preterm Infants in Relation to l-Thyroxine Supplementation

“…13 Median nerve SEPs have been studied extensively during the neonatal period. [27][28][29][30][31][32][33][34][35][36][37][38] The short-latency N 1 component, regarded to reflect the maturation of the nervous system, can be affected by many factors. As described in the literature, these include behavioral state, 30 medication, 31 cranial ultrasound abnormalities, 32-34 hyperbilirubinemia, 35 low birth weight, 36 adaptation to extrauterine life, 37 and prenatal exposure to betamethasone/thyrotropin-releasing factor.…”