“…32 Among four DNA bases (A, T, C, and G) C and G provide excellent binding sites for Ag + . 33 The nanoparticleligand complex exhibits many unusual properties, such as cobonding power, high affinity, extraordinary catalytic properties for signal enhancement, and dramatic intracellular stability, making it an intracellular therapeutic and diagnostic agent. 32b In this research, by use of bioinformatics tools, a specic aptamer for S. mutans was designed and optimized.…”