The spatial spillover effects of energy transition and trade openness on CO2 emissions

Ashraf, Junaid; Ashraf, Zeeshan; Javed, Aiman

doi:10.1016/j.enbuild.2023.113167

Cited by 20 publications

(2 citation statements)

References 76 publications

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“…34 In addition to genetically altered EPO production, factors such as residence at high altitudes and naturally increasing EPO secretion also represent risk factors for venous thrombosis and pulmonary thromboembolism. 35 36 These conditions can be mimicked in a mouse model through chronic hypoxia. 37…”

Section: Discussionmentioning

confidence: 99%

Differential Effects of Erythropoietin Administration and Overexpression on Venous Thrombosis in Mice

Stockhausen,

Kilani,

Schubert

et al. 2023

Thromb Haemost

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Background Deep vein thrombosis (DVT) is a common condition associated with significant mortality due to pulmonary embolism. Despite advanced prevention and anticoagulation therapy, the incidence of venous thromboembolism remains unchanged. Individuals with elevated hematocrit and/or excessively high erythropoietin (EPO) serum levels are particularly susceptible to DVT formation. We investigated the influence of short-term EPO administration compared to chronic EPO overproduction on DVT development. Additionally, we examined the role of the spleen in this context and assessed its impact on thrombus composition. Methods We induced ligation of the caudal vena cava (VCC) in EPO-overproducing Tg(EPO) mice as well as wildtype mice treated with EPO for two weeks, both with and without splenectomy. The effect on platelet circulation time was evaluated through FACS analysis, and thrombus composition was analyzed using immunohistology. Results We present evidence for an elevated thrombogenic phenotype resulting from chronic EPO overproduction, achieved by combining an EPO-overexpressing mouse model with experimental DVT induction. This increased thrombotic state is largely independent of traditional contributors to DVT, such as neutrophils and platelets. Notably, the pronounced prothrombotic effect of red blood cells (RBCs) only manifests during chronic EPO overproduction and is not influenced by splenic RBC clearance, as demonstrated by splenectomy. In contrast, short-term EPO treatment does not induce thrombogenesis in mice. Consequently, our findings support the existence of a differential thrombogenic effect between chronic enhanced erythropoiesis and exogenous EPO administration. Conclusion Chronic EPO overproduction significantly increases the risk of DVT, while short-term EPO treatment does not. These findings underscore the importance of considering EPO-related factors in DVT risk assessment and potential therapeutic strategies.

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Section: Discussionmentioning

confidence: 99%

Differential Effects of Erythropoietin Administration and Overexpression on Venous Thrombosis in Mice

Stockhausen,

Kilani,

Schubert

et al. 2023

Thromb Haemost

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show abstract

“…Due to the spatial effects[ 72 ] of ISU, the model (2) did not consider spatial effects. Compared to spatial lag models and spatial error models, the Spatial Durbin Model (SDM) incorporates both the spatial dependence effects of the independent and dependent variables, making it more general.…”

Section: Study Area Methods and Data Sourcesmentioning

confidence: 99%

Environmental regulation, land use efficiency and industrial structure upgrading: Test analysis based on spatial durbin model and threshold effect

Yu,

Zheng

2024

Heliyon

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A new look at the finance–environment nexus: How yield spread affects environmental quality in the United States

Bulut,

Apergis,

Isik

et al. 2024

Bus Strat Env

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Enhancing environmental quality is currently a key focus for policymakers. Furthermore, researchers are also prioritizing the investigation of novel variables that can influence environmental quality. The yield spread is commonly used as a leading indicator for business cycles in the macro‐finance literature, providing information about future expectations regarding business cycles. The yield spread also presents information about the borrowing costs of firms. None of the existing studies in the environmental economics literature has tested the impact of the yield spread on environmental quality, implying the level of the yield spread has not been considered a variable that can influence environmental quality. This study aims to fill this gap by providing evidence on the effect of yield spread (between 2‐ and 10‐year government bonds) on environmental quality in the United States from June 1976 to September 2023. The results indicate that an increase in the yield spread leads to a rise in environmental destruction. These results suggest two considerable consequences. First, optimistic expectations today lead to the overuse of resources and environmental destruction. Second, firms' higher borrowing costs may be forcing them to use less environmentally friendly production methods to offset more expensive financing costs and increase their profits. This study asserts that companies should enhance their environmental sensitivity, and policymakers should adopt a more proactive stance, based on the results of this study and other research that demonstrates the detrimental impacts of environmental regulation violations and poor environmental performances on companies' stock prices and financial performances.

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The spatial spillover effects of energy transition and trade openness on CO2 emissions

Cited by 20 publications

References 76 publications

Differential Effects of Erythropoietin Administration and Overexpression on Venous Thrombosis in Mice

Differential Effects of Erythropoietin Administration and Overexpression on Venous Thrombosis in Mice

Environmental regulation, land use efficiency and industrial structure upgrading: Test analysis based on spatial durbin model and threshold effect

A new look at the finance–environment nexus: How yield spread affects environmental quality in the United States

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