The specific dermatoses of pregnancy revisited and reclassified: Results of a retrospective two-center study on 505 pregnant patients

Ambros-Rudolph, Christina M.; Müllegger, Robert R.; Vaughan-Jones, Samantha A.; Kerl, Helmut; Black, Martin M.

doi:10.1016/j.jaad.2005.12.012

Cited by 341 publications

(185 citation statements)

References 26 publications

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“…: токсемическая сыпь беременных, токсическая эритема беременных), за-тем пруригинозный фолликулит беременных и вну-трипеченочный холестаз беременных. Пруриго бе-ременных Бенье, пруригинозный фолликулит бере-менных и атопический дерматит были объединены в группу «Атопическая сыпь беременных», так как главные клинические и патогистологические при-знаки их были идентичны [19][20][21][22][23][24][25].…”

Section: исторический обзорunclassified

A view of the problem of pregnancy-specific skin dermatoses. Part I

Khachikian¹,

Karapetian²

2014

Klin. dermatol. venerol.

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Section: исторический обзорunclassified

A view of the problem of pregnancy-specific skin dermatoses. Part I

Khachikian¹,

Karapetian²

2014

Klin. dermatol. venerol.

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“…The generally accepted classification suggested by Ambros-Rudolph et al [1] is used to describe skin diseases typical for pregnancy. It includes the characteristics of all types of dermatoses occurring only during pregnancy, i.e.…”

Section: Introductionmentioning

confidence: 99%

“…It includes the characteristics of all types of dermatoses occurring only during pregnancy, i.e. prurigo of pregnancy, polymorphic eruption of pregnancy, pemphigoid gestationis (PG), and intrahepatic cholestasis of pregnancy [1].…”

Section: Introductionmentioning

confidence: 99%

Pemphigoid gestationis – a rare dermatosis of the prenatal period. Case report

Skutil¹,

Roztoczyński²

2016

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Introduction. Most skin lesions during pregnancy are associated with hormonal changes. Pemphigoid (herpes) gestationis (PG) is a significant dermatosis of the prenatal period reflecting pathology affecting the mother and fetus. Objective. The aim of the study was to present a PG case, a rare pregnancy dermatosis with a severe clinical outcome during the postpartum period. Case report. We present a case of a patient in whom skin lesions with tense blisters occurred at the 40 th week of pregnancy. Herpes gestationis -a rare skin disease -was diagnosed based on the clinical picture. During the first days of puerperium, because of an aggressive disease course, the patient was transferred to a reference centre for skin disease treatment. She was given corticosteroid therapy, which brought the expected results. Conclusions. Pemphigoid gestationis is a rare and serious dermatosis of the prenatal period. Although the treatment of such diseases is the dermatologists' task, obstetricians are responsible for diagnosis and for fetal monitoring considering placental pathology. STRESZCZENIEWprowadzenie. Większość zmian skórnych w okresie ciąży wiąże się ze zmianami gospodarki hormonalnej. Pemfigoid (opryszczka) ciężar-nych jest ważną dermatozą okresu prenatalnego odzwierciedlającą patologię toczącą się w jednostce matczyno-płodowej. Cel pracy. Przedstawienie przypadku pemfigoidu ciężarnych, rzadkiej dermatozy ciążowej, o ciężkim przebiegu klinicznym w okresie połogu. Opis przypadku. Przedstawiamy przypadek pacjentki, u której w 40. tygodniu ciąży zaobserwowano zmiany skórne w postaci napiętych pę-cherzy, co pozwoliło na podstawie obrazu klinicznego rozpoznać rzadką chorobę skóry, jaką jest opryszczka ciężarnych. W pierwszych dniach połogu ze względu na agresywny przebieg choroby pacjentka została przekazana do ośrodka referencyjnego leczenia chorób skóry. Zastosowana tam terapia glikokortykosteroidami przyniosła zamierzony efekt. Wnioski. Pemfigoid ciężarnych jest rzadką dermatozą okresu prenatalnego, której terapię prowadzą dermatolodzy, a zadaniem położników jest rozpoznanie choroby i monitorowanie stanu płodu z uwzględnie-niem faktu patologii łożyska.Pemphigoid gestationis -a rare dermatosis of the prenatal period. Case report Pemfigoid ciężarnych -rzadka dermatoza okresu prenatalnego. Opis przypadku

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“…Population-based studies have reported an annual incidence ranging between 0.5 and 2.0 cases per 1 million people in France, Kuwait and Germany [3–5]. In a retrospective study, PG was found in 4.2% of 505 pregnant patients evaluated in university-based dermatologic pregnancy clinics [6]. Based on the current epidemiological data PG is estimated to occur in one out of about 40,000-50,000 pregnancies [7] with no difference in racial distribution [8,9].…”

Section: Introductionmentioning

confidence: 99%

“…The most important differential diagnosis alternatives for PG are the other specific dermatoses of pregnancy which include atopic eruption of pregnancy (AEP), polymorphic eruption of pregnancy (PEP) and intrahepatic cholestasis of pregnancy (ICP) [6,36–40]. AEP is the most common pregnancy-specific skin disease, which typically appears in the first and second trimesters [40].…”

Section: Introductionmentioning

confidence: 99%

Gestational pemphigoid

Huilaja

Mäkikallio

Tasanen

2014

Orphanet J Rare Dis

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Gestational pemphigoid (pemphigoid gestationis, PG) is a rare autoimmune skin disorder occurring characteristically during pregnancy. Autoantibodies against placental BP180 (also known as BPAG2 or collagen XVII) cause damage to the skin basement membrane, resulting in severe itching and blistering rash over the body and the extremities. The diagnosis of PG is confirmed by immunofluorescence analysis of a skin biopsy, while serum levels of pemphigoid antigen BP180 antibody can be used to assess disease activity. PG with mild symptoms can be treated with topical corticosteroids, while oral corticosteroids are the mainstay in treatment of severe PG. PG usually flares up at the time of delivery, and resolves spontaneously shortly after. However, relapses in subsequent pregnancies are common. As PG has been linked to the risk of prematurity and fetal growth restriction, prenatal monitoring jointly by a dermatologist and an obstetrician is recommended. Mothers should also be informed of the potential risk of re-activation of the disease in subsequent pregnancies and during hormonal contraception.

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The specific dermatoses of pregnancy revisited and reclassified: Results of a retrospective two-center study on 505 pregnant patients

Cited by 341 publications

References 26 publications

A view of the problem of pregnancy-specific skin dermatoses. Part I

A view of the problem of pregnancy-specific skin dermatoses. Part I

Pemphigoid gestationis – a rare dermatosis of the prenatal period. Case report

Gestational pemphigoid

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