The Specific Gravity Adjustment in Urinalysis

Elkins, Hervey B.; Pagnotto, Leonard D.

doi:10.1080/00039896.1969.10665525

Cited by 16 publications

(16 citation statements)

References 3 publications

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“…They collected urine the previous night and brought it along for estimation of metal ion output. A 12-hour collection was used rather than a 24-hour collection, because patient compliance is better [1,11] with a 12-hour collection. Twenty-seven of the 31 patients provided a 12-hour urine sample for metal ion analysis.…”

Section: Methodsmentioning

confidence: 99%

Early Markers of Nephrotoxicity in Patients With Metal-on-metal Hip Arthroplasty

Corradi

Daniel

Ziaee

et al. 2011

Clinical Orthopaedics &Amp; Related Research

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Section: Methodsmentioning

confidence: 99%

Early Markers of Nephrotoxicity in Patients With Metal-on-metal Hip Arthroplasty

Corradi

Daniel

Ziaee

et al. 2011

Clinical Orthopaedics &Amp; Related Research

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“…In reflection of concerns about apparent differences in urine density among samples, urinary levels of creatinine (CR) (Jackson 1966) and specific gravity (SG) (Buchwald 1964;Rainsford and Lloyd Davies 1965;Elkins et al 1974) have been employed as common denominators of analyte levels in urine to ''adjust'' or ''correct'' for urine density.…”

Section: Introductionmentioning

confidence: 99%

Decreases in urine specific gravity and urinary creatinine in elderly women

Moriguchi

Ezaki

Tsukahara

et al. 2005

Int Arch Occup Environ Health

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“…working habits as well as to personal differences Many writers have found an association between in the metabolic effect of the lead absorbed. The biochemical tests of lead absorption and lead-in-air magnitude of such personal differences in work-concentration, but regression equations andestimates ing habits appears to be unknown (Legge and of some of the sources ofvariation of the biochemical 202 tests are not known (e.g., Dreessen et al, 1941;Elkins, 1959;Kehoe, 1961). The benefit obtained from correcting urinary lead estimations for specific gravity is controversial (Barnes, 1939; Levine and Fahy, 1945;Molyneux, 1964;Elkins and Pagnotto, 1965;Ellis, 1966).…”

mentioning

confidence: 99%

An investigation of lead absorption in an electric accumulator factory with the use of personal samplers

Williams

King

Walford

1969

Occupational and Environmental Medicine

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1969). Brit. J. industr. Med., 26,[202][203][204][205][206][207][208][209][210][211][212][213][214][215][216]. An investigation of lead absorption in an electric accumulator factory with the use of personal samplers. Thirty-nine lead workers and controls, in stable conditions of exposure, each wore personal lead-in-air samplers daily for two weeks. During the second week samples for blood lead, urinary lead, urinary coproporphyrin, urinary 8-aminolevulinic acid (ALA), the punctate basophil count, and haemoglobin were taken daily. Duplicate estimations were made on one day.The lead exposures of men doing almost identical jobs differed by ratios of up to four to one. This could be attributed only to personal differences in working habits.The correlation coefficients and regression equations of the biochemical tests with lead-inair and with each other were determined. The-mean values and 95 % confidence limits of single determinations of some of the biochemical tests corresponding to the two commonly accepted TLVs of lead-in-air (0-20 and 0 15 mg./m.3) were calculated from the regression equations.For each biochemical test the variation due to analytical error, the variation from day to day within subjects and the residual variation about the regression on lead-in-air were calculated. Previous estimates of the latter are not known. Excessive confidence may be placed in an index of exposure due to its low coefficient of variation within subjects unless the coefficient of variation between subjects about regression is taken into account.The correction for specific gravity of estimations of lead and ALA in spot samples of urine was found to reduce slightly the residual variation between subjects about the regression on lead-in-air and to increase the correlations with lead-in-air and with the other biochemical tests, but these changes were not statistically significant.The modified method used for estimating blood lead and urinary lead is described and validated.

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The Specific Gravity Adjustment in Urinalysis

Cited by 16 publications

References 3 publications

Early Markers of Nephrotoxicity in Patients With Metal-on-metal Hip Arthroplasty

Early Markers of Nephrotoxicity in Patients With Metal-on-metal Hip Arthroplasty

Decreases in urine specific gravity and urinary creatinine in elderly women

An investigation of lead absorption in an electric accumulator factory with the use of personal samplers

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