This study compares the features of homicide-suicide in Russia and Pakistan. To understand this, we conducted a content analysis of news reports about homicide-suicide published in Pakistani and Russian newspapers between March 2020 and May 2023. We identified 35 and 104 homicide-suicide cases in Pakistani and Russian media, respectively. Men were three to five times more likely to commit homicide-suicides than women (3.16: 1 in Russia; 4.83: 1 in Pakistan). Accounting for over 65.73% of all homicide-suicides, spousal homicide-suicides and filicide-suicide were the most common homicide-suicides in both regions. Filicide-suicides were more often done by Russian women and extra-family homicide-suicides by Pakistani women. Reasons for homicide-suicides in Pakistani women were divorce or separation and in Russian women – mental disorders. With the difference of homicide in the victims, Pakistani victims were aged 15–30 years, while Russian were 31–45 years and 46 years and older. There were more similarities in homicide-suicides than differences.