The spectrum of biopsy-proven renal diseases in Korea

Lim, Beom Jin

doi:10.23876/j.krcp.20.019

Cited by 1 publication

(1 citation statement)

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“…It has been reported that kidney involvement in SLE was more frequent in several races including Asians with unclear mechanisms [ 29 ]. A study from Korea consistently revealed that LN was the most common type of SGN [ 30 ]. There was a statistically significant decrease in its proportion between 2008 and 2013 compared to 2014 and 2018 in our study.…”

Section: Discussionmentioning

confidence: 99%

Changes in the spectrum of biopsy-proven renal diseases over 11 years: a single-center study in China

Wang,

Zhang,

Yuan

et al. 2024

Renal Failure

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Background There have been some shifts in the frequency and distribution of biopsy-proven renal diseases in China over recent years. The aim of the study was to investigate the changing spectrum of renal diseases from the view of kidney biopsy data in a single center of China. Methods and results A total of 10,996 cases of native renal biopsies from patients aged ≥15 years old in Huashan Hospital, Fudan University, between 2008 and 2018 were analyzed retrospectively. The results showed that primary glomerular nephropathy (PGN) remained the most common biopsy-proven renal disease (69.42% of total), with IgA nephropathy (IgAN) accounting for 44.40% of PGN, membranous nephropathy (MN) for 28.55%, minimal change disease (MCD) for 13.26% and focal segmental glomerulosclerosis (FSGS) for 8.00%. During the study period, the proportion of MN in PGN appeared an increasing tendency, while that of IgAN and MCD remained stable and that of FSGS showed a decline. Secondary glomerular nephropathy (SGN) constituted 21.54% of total cases, among which the leading two diseases were lupus nephritis (LN) and Henoch-Schonlein purpura nephritis (HSN) which accounted for 41.08% and 19.11% respectively. Conclusions The 11-year retrospective study revealed that PGN was the predominant histologic diagnosis among patients undergoing renal biopsy and the most frequent type of PGN remained to be IgAN, followed by MN which increased dramatically.

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Section: Discussionmentioning

confidence: 99%