The spectrum of focal epithelial hyperplasia-a report of two cases

Cerejeira, André; Gomes, Nathália Matos; Melo, Daniel Souza de; Sobrinho‐Simões, Joana; Azevedo, F; Lisboa, Cármen

doi:10.5070/d327654055

Cited by 1 publication

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“…Although the majority of the published reports were female cases, 5,6 no gender predilection for MEH was found 18,19 …”

Section: Discussionmentioning

confidence: 98%

“…Although the majority of the published reports were female cases, 5,6 no gender predilection for MEH was found. 18,19 MEH appears in Eskimos, Inuits and Indians in central, north and south America 20 ; however, its prevalence rate is low in Europe, and Asian countries. 1,21 There are genetic and ethnic associations with the presence of the disease side by side with the confirmed HPV aetiology.…”

Section: Discussionmentioning

confidence: 99%

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A severe manifestation of extensive multifocal epithelial hyperplasia (Heck's disease) and the role of CO₂ laser as a treatment modality: A case report

et al. 2023

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Heck's disease or multifocal epithelial hyperplasia (MEH) is an uncommon asymptomatic contagious oral condition, usually attributed to human papillomavirus (HPV) infection. It manifests as several smooth papules and nodules in the oral mucosa. The disease has a good prognosis, as it is spontaneously regressing, but some cases persist and affect the quality of the patient's life, requiring therapeutic intervention. We present an unusual case of extensive multifocal epithelial hyperplasia. To the best of our knowledge, this is the first case to be reported with this severity and widespreadness of the lesions. A 14‐ year‐old girl was referred to the department of oral medicine at the faculty of dental medicine, with a chief complaint of numerous nodules and papules, appeared since she was 6 years old. The diagnosis of Heck's disease was confirmed depending on clinical characteristics, histopathological examination and immunohistochemical (IHC) staining. Human immunodeficiency virus (HIV) antibodies test and enzyme‐linked immunosorbent assay (ELISA) for human papillomavirus Immunoglobulin G (IgG) were performed. Depending on the extensive clinical situation, the decision was made to treat the patient using carbon dioxide (CO2) laser. Heck's disease is a human papillomavirus‐related oral condition. The diagnosis can be confirmed depending on both clinical and histopathological characteristics in addition to immunohistochemical staining. In this case, CO2 laser showed good functional and aesthetic results that reflected positively on the quality of the patient's life.

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“…Although the majority of the published reports were female cases, 5,6 no gender predilection for MEH was found 18,19 …”

Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

A severe manifestation of extensive multifocal epithelial hyperplasia (Heck's disease) and the role of CO₂ laser as a treatment modality: A case report

et al. 2023

View full text Add to dashboard Cite

show abstract

The spectrum of focal epithelial hyperplasia-a report of two cases

Cited by 1 publication

References 4 publications

A severe manifestation of extensive multifocal epithelial hyperplasia (Heck's disease) and the role of CO₂ laser as a treatment modality: A case report

A severe manifestation of extensive multifocal epithelial hyperplasia (Heck's disease) and the role of CO₂ laser as a treatment modality: A case report

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The spectrum of focal epithelial hyperplasia-a report of two cases

Cited by 1 publication

References 4 publications

A severe manifestation of extensive multifocal epithelial hyperplasia (Heck's disease) and the role of CO2 laser as a treatment modality: A case report

A severe manifestation of extensive multifocal epithelial hyperplasia (Heck's disease) and the role of CO2 laser as a treatment modality: A case report

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A severe manifestation of extensive multifocal epithelial hyperplasia (Heck's disease) and the role of CO₂ laser as a treatment modality: A case report

A severe manifestation of extensive multifocal epithelial hyperplasia (Heck's disease) and the role of CO₂ laser as a treatment modality: A case report