IntroductionParkinson disease (PD) is a chronic progressive disease (1). Parkinson patients frequently have nonmotor disorders such as constipation, sexual dysfunction, and lower urinary tract symptoms, in addition to motor disorders (2). Nonmotor disorders frequently observed in PD patients include bladder dysfunctions like urgency and frequent urination (3). The brain pathology causing bladder dysfunction includes dopamine changes in the basal ganglia-frontal circuit that normally suppresses the urination reflex (1). Animal studies have shown a correlation between dopaminergic degeneration in the brain and overactive bladder (4).The incidence of urinary complaints observed with PD is reported as 93% (1,5). Among the most commonly reported complaints are irritative bladder symptoms like urgency, leaking, and frequent urination. Bladder dysfunction increases related to the severity of PD (5). Some studies have not found this correlation (1). Though PD patients generally respond very well to dopaminergic medications, urological complaints generally do not respond to medication treatment (6). Anticholinergic medications frequently used for urinary complaints may disrupt cognitive functions in older patients and it should be remembered that they may cause serious results (7).The aim of this study is to investigate whether there is a difference between urinary complaints observed with PD and disruption of quality of life caused by these complaints in patients and healthy individuals. An additional aim was to identify whether urinary complaints observed with PD are affected by characteristics like sex, age, disease duration, and severity.
Materials and methodsThis study was completed at the Ordu University Hospital with cooperation between the urology and neurology clinics. This study included 39 patients applying to the neurology clinic between January 2013 and June 2014 with Background/aim: The aim of this study is to research whether urinary symptoms and disruption of quality of life observed in Parkinson disease patients are different than those of their healthy peers. Additionally, whether these complaints were affected by characteristics such as age at onset of Parkinson disease, sex, disease duration, and severity was investigated. Materials and methods: This study comprised a total of 79 individuals, 39 Parkinson patients and a control group of 40 individuals. Parkinson diagnosis was provided by a neurology expert according to the UK Parkinson's Disease Society Brain Bank Criteria. All patients were evaluated by a urologist with the International Prostate Symptom Score (IPSS) and an overactive bladder (OAB) questionnaire.Results: Compared with the control group, the Parkinson patient group had statistically significantly higher rates of urological complaints (P < 0.001), irritative symptoms (P < 0.001), voiding symptoms (P < 0.001), OAB score (P < 0.001), IPSS total score (P = 0.007), and treatment requirements (P < 0.001).
Conclusion:Urologic complaints were observed more frequently in the Parkinson patient g...